product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD8
catalog :
MBS215242
quantity :
0.1 ml
price :
205 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS215242
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD8
products short name :
CD8
other names :
T-cell surface glycoprotein CD8 alpha chain isoform 1; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 alpha chain; CD8 antigen, alpha polypeptide (p32); Leu2 T-lymphocyte antigen; OKT8 T-cell antigen; T cell co-receptor; T-cell antigen Leu2; T-lymphocyte differentiation antigen T8/Leu-2; CD8a molecule; T-lymphocyte differentiation antigen T8/Leu-2; CD_antigen: CD8a
products gene name :
CD8
other gene names :
CD8A; CD8A; CD8; MAL; p32; Leu2; MAL
uniprot entry name :
CD8A_HUMAN
clonality :
Monoclonal
isotype :
IgG2b
clone :
4B11
host :
Mouse
sequence length :
235
form :
Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
tested application :
Immunohistology Frozen, Immunohistology Paraffin*
app notes :
Immunohistology - Frozen: Minimum Dilution: 1/20; Maximum Dilution: 1/40;. Immunohistology - Paraffin: Minimum Dilution: 1/20; Maximum Dilution: 1/40; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Tris/EDTA buffer pH 8.0 is recommended for this purpose.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide
other info2 :
Immunogen: Synthetic peptide derived from CD8 alpha chain sequence. Histology Positive Control Tissue: Human Tonsil. Fusion Partners: Spleen cells from immunised mice were fused with cells of a mouse p3-NS1-Ag4-1 myeloma cell line. Target Species: Human
products description :
Mouse anti Human CD8 antibody, clone 4B11 recognizes the human CD8 cell surface antigen, a 32kDa glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. Mouse anti Human CD8 antibody, clone 4B11 has been reported as being suitable for use in Western blotting.
ncbi gi num :
225007536
ncbi acc num :
NP_001139345.1
ncbi gb acc num :
NM_001145873.1
ncbi mol weight :
30,214 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Antigen Processing And Presentation Pathway 83074!!Antigen Processing And Presentation Pathway 485!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018!!Hematopoietic Cell Lineage Pathway 83078!!Hematopoietic Cell Lineage Pathway 489!!IL12-mediated Signaling Events Pathway 137922!!Immune System Pathway 106386
ncbi summary :
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
size :
0.1 ml
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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