product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD16
catalog :
MBS215241
quantity :
0.1 ml
price :
205 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS215241
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD16
products short name :
CD16
other names :
low affinity immunoglobulin gamma Fc region receptor III-B isoform 2; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-B; Fc-gamma receptor IIIb (CD 16); fc-gamma RIII-beta; fc-gamma RIIIb; igG Fc receptor III-1; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD_antigen: CD16b
products gene name :
CD16
other gene names :
FCGR3B; FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb; CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb
uniprot entry name :
FCG3B_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
2H7
host :
Mouse
sequence length :
233
specificity :
This clone recognises the human CD16 cell surface antigen expressed by granulocytes, NK cells, macrophages and a subset of T-cells.
form :
Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Paraffin*
app notes :
Immunohistology - Paraffin: Minimum Dilution: 1/20; Maximum Dilution: 1/40; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
other info1 :
Perservative Stabilisers: 0.09 % Sodium Azide
other info2 :
Immunogen: Recombinant protein corresponding to the external domain of the CD16 molecule, common to both the transmembrane form and the GPI-linked form. Histology Positive Control Tissue: Tonsil. Fusion Partners: Spleen cells from immunised mice were fused with cells of a mouse p3-NS1-Ag4-1 myeloma cell line. Target Species: Human
products description :
This clone recognises the human CD16 cell surface antigen expressed by granulocytes, NK cells, macrophages and a subset of T-cells.
ncbi gi num :
132814489
ncbi acc num :
NP_000561.3
ncbi gb acc num :
NM_000570.4
ncbi mol weight :
26,216 Da
ncbi pathways :
Leishmaniasis Pathway 144181!!Leishmaniasis Pathway 144028!!Natural Killer Cell Mediated Cytotoxicity Pathway 83079!!Natural Killer Cell Mediated Cytotoxicity Pathway 490!!Osteoclast Differentiation Pathway 193147!!Osteoclast Differentiation Pathway 193096!!Phagosome Pathway 153910!!Phagosome Pathway 153859!!Staphylococcus Aureus Infection Pathway 172846!!Staphylococcus Aureus Infection Pathway 171867
ncbi summary :
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
size :
0.1 ml
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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