product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD68
catalog :
MBS215240
quantity :
0.1 ml
price :
205 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS215240
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD68
products short name :
CD68
other names :
macrosialin isoform B; Macrosialin; macrosialin; CD68 antigen; macrophage antigen CD68; scavenger receptor class D, member 1; CD68 molecule; Gp110; CD_antigen: CD68
products gene name :
CD68
other gene names :
CD68; CD68; GP110; LAMP4; SCARD1; N/A
uniprot entry name :
CD68_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
514H12
host :
Mouse
sequence length :
327
form :
Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.
tested application :
Immunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin*
app notes :
Immunohistology - Paraffin: Minimum Dilution: 1/40; Maximum Dilution: 1/80; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. EDTA buffer pH 8.0 is recommended for this purpose. N.B. The epitope recognised by clone 514H12 is sensitive to peroxide. It is therefore recommended that any peroxidase-blocking steps be performed after incubation with this antibody .
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide
other info2 :
Immunogen: Fusion protein corresponding to external domain of human CD68. Histology Positive Control Tissue: Human Tonsil. Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse p3-NS1-Ag4-1 myeloma cell line. Target Species: Human
products description :
Mouse anti Human CD68 antibody, clone 514H12 recognizes the human CD68 cell surface antigen, a 110kDa glycoprotein primarily expressed by macrophages and monocytes.
ncbi gi num :
91199550
ncbi acc num :
NP_001035148.1
ncbi gb acc num :
NM_001040059.1
uniprot acc num :
P34810
ncbi mol weight :
34,654 Da
ncbi pathways :
Lysosome Pathway 99052!!Lysosome Pathway 96865
ncbi summary :
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
size :
0.1 ml
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!