MyBioSource

antibody

MOUSE ANTI HUMAN CD10

MBS215235

0.1 ml

205 USD

monoclonal

mouse

human

MBS215235

Antibody

MOUSE ANTI HUMAN CD10

CD10

neprilysin; Neprilysin; neprilysin; atriopeptidase; common acute lymphocytic leukemia antigen; enkephalinase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase); membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; neprilysin-390; neprilysin-411; neutral endopeptidase 24.11; skin fibroblast elastase; membrane metallo-endopeptidase; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD_antigen: CD10

CD10

MME; MME; NEP; SFE; CD10; CALLA; EPN; CALLA; NEP; Neutral endopeptidase; SFE

NEP_HUMAN

Monoclonal

IgG1

56C6

Mouse

750

Tissue Culture Supernatant - liquid

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.

Immunohistology Frozen, Immunohistology Paraffin*

Immunohistology - Frozen: Maximum Dilution: 1/80;. Immunohistology - Paraffin: Maximum Dilution: 1/80; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.

Perservative Stabilisers: 0.09% Sodium Azide

Immunogen: Recombinant human CD10. Histology Positive Control Tissue: Tonsil, Intestine or kidney. Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse p3-NS1-Ag4-1 myeloma cell line. Target Species: Human

Mouse anti Human CD10 antibody, clone 56C6 recognizes the human CD10 cell surface antigen, a 100kDa glycoprotein also known as CALLA (common acute lymphoblastic leukaemia antigen). CD10 is expressed on a variety of cell types, including immature and germinal centre B cells, lymphoblastic leukaemia cells and also on the brush border of kidney epithelial cells.

116256329

NP_000893.2

NM_000902.3

P08473

85,514 Da

Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Hematopoietic Cell Lineage Pathway 83078!!Hematopoietic Cell Lineage Pathway 489!!Metabolism Of Angiotensinogen To Angiotensins Pathway 685555!!Metabolism Of Proteins Pathway 106230!!Peptide Hormone Metabolism Pathway 771603!!Protein Digestion And Absorption Pathway 172847!!Protein Digestion And Absorption Pathway 171868

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008]

0.1 ml

205 USD