MOUSE ANTI MOUSE CD44:FITC | MyBioSource MBS214726 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MOUSE ANTI MOUSE CD44:FITC

catalog :

MBS214726

quantity :

0.025 mg

price :

175 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

[5035-41.1D]

reactivity :

mouse

application :

flow cytometry, FACS

more info or order :

MyBioSource product webpage

image

image 1 :

Staining of mouse spleen cells with Mouse anti Mouse CD44:FITC (MBS210594)

product information

catalog number :

MBS214726

products type :

Antibody

products full name :

MOUSE ANTI MOUSE CD44:FITC

products short name :

[CD44]

products name syn :

[H-CAM, PGP-1]

other names :

[CD44 antigen isoform c; CD44 antigen; CD44 antigen; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; PGP-I; extracellular matrix receptor III; hermes antigen; hyaluronate receptor; lymphocyte antigen 24; phagocytic glycoprotein 1; phagocytic glycoprotein I; CD44 antigen; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Lymphocyte antigen 24; Ly-24; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD_antigen: CD44]

products gene name :

[CD44]

other gene names :

[Cd44; Cd44; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109; Ly-24; ECMR-III; Ly-24; PGP-1; PGP-I]

uniprot entry name :

CD44_MOUSE

clonality :

Monoclonal

isotype :

IgG1

clone :

[5035-41.1D]

host :

Mouse

sequence length :

363

specificity :

Ly24.2 found on >90% bone marrow cells and spleen cells, 56% of thymus cells and 90% of lymph node cells.This antibody recognises the following strains of mice:- C57BL/6, C57BL/10, C57/L, C58A, AKR, 129, SJL, NZB, C3H, CE, CBA/H.

form :

FITC. Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

concentration :

IgG concentration 0.1mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

Flow cytometry (FC/FACS)

app notes :

Flow Cytometry: Use 10ul of the suggested working dilution to label 10 6 cells or 100ul whole blood . Suggested Dilution: . Flow Cytometry: Neat

image1 heading :

Testing Data

other info1 :

Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

other info2 :

Immunogen: Spleen cells from B6PL-Ly-2a / Ly-3a B6-Ly-1a mice. Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse P3-NS1-1-Ag4 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Mouse. Max Ex/Em: Fluorophore: FITC. Excitation(nm): 490. Emission (nm): 520

products description :

Ly24.2 found on >90% bone marrow cells and spleen cells, 56% of thymus cells and 90% of lymph node cells. This antibody recognises the following strains of mice:- C57BL/6, C57BL/10, C57/L, C58A, AKR, 129, SJL, NZB, C3H, CE, CBA/H.

ncbi gi num :

85540468

ncbi acc num :

NP_001034240.1

ncbi gb acc num :

NM_001039151.1

uniprot acc num :

P15379

ncbi mol weight :

39,999 Da

ncbi pathways :

Cell Surface Interactions At The Vascular Wall Pathway (1110059); Cytokine Signaling In Immune System Pathway (1110778); Defective B3GAT3 Causes JDSSDHD Pathway (1111411); Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway (1111415); Defective B4GALT7 Causes EDS, Progeroid Type Pathway (1111410); Defective CHST14 Causes EDS, Musculocontractural Type Pathway (1111414); Defective CHST3 Causes SEDCJD Pathway (1111413); Defective CHST6 Causes MCDC1 Pathway (1111416); Defective CHSY1 Causes TPBS Pathway (1111412); Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway (1111417)

uniprot summary :

CD44: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Interacts with PKN2. Interacts with HA, as well as other glycosaminoglycans, collagen, laminin, and fibronectin via its N-terminal segment. Interacts with ANK, the ERM proteins (VIL2, RDX and MSN), and NF2 via its C-terminal segment. Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells. 19 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, misc.; Cell adhesion; Motility/polarity/chemotaxis. Cellular Component: Golgi apparatus; focal adhesion; protein complex; cell surface; membrane; basolateral plasma membrane; apical plasma membrane; cytoplasm; plasma membrane; integral to membrane; nucleus; external side of plasma membrane. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; cytokine binding; hyaluronic acid binding; phosphoprotein binding; protein kinase binding; hyalurononglucosaminidase activity; epidermal growth factor receptor binding. Biological Process: cell migration; Wnt receptor signaling pathway; positive regulation of heterotypic cell-cell adhesion; positive regulation of neutrophil apoptosis; negative regulation of caspase activity; positive regulation of peptidyl-serine phosphorylation; hyaluronan catabolic process; negative regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of mature B cell apoptosis; ureteric bud branching; regulation of cell growth; cell adhesion; healing during inflammatory response; neurite development; positive regulation of adaptive immune response; negative regulation of apoptosis

size1 :

0.025 mg

price1 :

175 USD

more info or order :

MyBioSource product webpage