catalog number :
MBS214601
products full name :
MOUSE ANTI HUMAN COMPLEMENT FACTOR H
products short name :
COMPLEMENT FACTOR H
other names :
complement factor H isoform a; Complement factor H; complement factor H; H factor 1 (complement); H factor 2 (complement); adrenomedullin binding protein; age-related maculopathy susceptibility 1; beta-1-H-globulin; beta-1H; complement factor H, isoform b; factor H-like 1; complement factor H; H factor 1
other gene names :
CFH; CFH; FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; HF; HF1; HF2
uniprot entry name :
CFAH_HUMAN
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Immunoprecipitation (IP), Radioimmunoassays (RIA), Western Blot (WB)
app notes :
ELISA: Minimum Dilution: 1/50; Maximum Dilution: 1/200
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
other info2 :
Immunogen: Human complement factor H. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the NS-O mouse myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human Complement Factor H antibody, clone OX-23 recognizes human serum complement protein factor H (155kD). It also recognizes a 43-49kD truncated form of factor H present at low level (1-5ug/ml) in plasma and urine.
ncbi acc num :
NP_000177.2
ncbi gb acc num :
NM_000186.3
ncbi mol weight :
51,034 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway 83073!!Complement And Coagulation Cascades Pathway 484!!Complement Cascade Pathway 106405!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Regulation Of Complement Cascade Pathway 576254!!Staphylococcus Aureus Infection Pathway 172846!!Staphylococcus Aureus Infection Pathway 171867
ncbi summary :
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]