antibody

MOUSE ANTI RABIES VIRUS GLYCOPROTEIN

MBS214580

0.2 mg

440 USD

monoclonal

mouse

nonconjugated

1C5

ELISA, immunocytochemistry, enzyme immunoassay

Antibody

MOUSE ANTI RABIES VIRUS GLYCOPROTEIN

RABIES VIRUS GLYCOPROTEIN

Monoclonal

IgG2a

1C5

Mouse

Purified. Purified IgG - liquid

IgG concentration 1.0mg/ml

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

Immunohistology Frozen, ELISA (EIA), Functional Assays (FN), Immunofluorescence (IF)

Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Purified rabies virus. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cells. Buffer Solution: Phosphate buffered saline. Target Species: Viral

Mouse anti Rabies Virus Glycoprotein antibody, clone 1C5 recognizes the glycoprotein of rabies virus, a Lyssavirus that causes rabies in mammals. The virus is found in the saliva of infected animals and is mostly spread though bites. The virus then travels though the peripheral nervous system to the central nervous system. Once it reaches the brain it causes acute encephalitis. Symptoms include paralysis, cerebral dysfunction, anxiety, insomnia, confusion, anger, paranoia, terror and hallucination. The production of a large amount of saliva, the inability to speak or swallow and associated hydrophobia is also common in the later stages of the disease. The time between exposure to the virus and onset of symptoms can range from about 2 weeks to several months. Once symptoms appear, death is virtually inevitable. However, the disease can be effectively treated by post-exposure prophylaxis, through vaccination, provided this is done as soon as possible. Mouse anti Rabies Virus Glycoprotein antibody, clone 1C5 recognizes the purified glycoprotein of the rabies virus as well as the native virus. It has been shown to react with intact infected BHK cells and has therapeutic effect on infected mice. The antibody has virus-neutralising activity with several rabies virus strains such as CVS, Lagos bat, Mokola, Flury LEP and Duvenhage.

0.2 mg

440 USD