product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MOUSE INTERLEUKIN-6:Preservative Free
catalog :
MBS214544
quantity :
0.1 mg
price :
390 USD
clonality :
monoclonal
host :
rat
reactivity :
mouse
application :
enzyme immunoassay, ELISA
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS214544
products type :
Antibody
products full name :
RAT ANTI MOUSE INTERLEUKIN-6:Preservative Free
products short name :
IL-6
other names :
interleukin-6; Interleukin-6; interleukin-6; B-cell hybridoma growth factor; interleukin HP-1; interleukin 6; B-cell hybridoma growth factor; Interleukin HP-1
other gene names :
Il6; Il6; Il-6; Il-6; IL-6
uniprot entry name :
IL6_MOUSE
clonality :
Monoclonal
isotype :
IgG1
clone :
6B4 IGH 54
host :
Rat
sequence length :
211
specificity :
This item is specific for mouse IL-6 (interleukin-6), a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts, which acts as the principle inducer of the acute phase response in the liver. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue. Clone 6B4 IGH 54 can be used to neutralise the activity of 50pg/ml of recombinant mouse IL-6 by >95% in a functional assay.
form :
Preservative Free. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Functional Assays (FN)
app notes :
Functional Assays: Maximum Dilution: 3ug/ml
other info1 :
Preparation: Purified IgG prepared by affinity chromatography on protein G
other info2 :
Immunogen: Natural partially purified mouse IL-6. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
MBS214544 is specific for mouse IL-6 (interleukin-6), a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts, which acts as the principle inducer of the acute phase response in the liver. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue. Clone 6B4 IGH 54 can be used to neutralise the activity of 50pg/ml of recombinant mouse IL-6 by >95% in a functional assay.
ncbi gi num :
13624311
ncbi acc num :
NP_112445.1
ncbi gb acc num :
NM_031168.1
uniprot acc num :
P08505
ncbi mol weight :
24,384 Da
ncbi pathways :
ARMS-mediated Activation Pathway 1110440!!Activated TLR4 Signalling Pathway 1110727!!Adipogenesis Pathway 198299!!African Trypanosomiasis Pathway 194387!!African Trypanosomiasis Pathway 194323!!Amoebiasis Pathway 167330!!Amoebiasis Pathway 167191!!Androgen Receptor Signaling Pathway 198319!!Axon Guidance Pathway 1111058!!Cellular Senescence Pathway 1111543
size :
0.1 mg
price :
390 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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