This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN TROPONIN C
catalog :
MBS214522
quantity :
0.2 mg
price :
400 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1A2
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
product information
catalog number :
MBS214522
products type :
Antibody
products full name :
MOUSE ANTI HUMAN TROPONIN C
products short name :
TROPONIN C
other names :
troponin C, slow skeletal and cardiac muscles; Troponin C, slow skeletal and cardiac muscles; troponin C, slow skeletal and cardiac muscles; cardiac troponin C; slow twitch skeletal/cardiac muscle troponin C; troponin C1, slow; troponin C type 1 (slow)
other gene names :
TNNC1; TNNC1; TNC; TN-C; TNNC; CMD1Z; CMH13; TNNC; TN-C
uniprot entry name :
TNNC1_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
1A2
host :
Mouse
sequence length :
161
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
other info2 :
Immunogen: Human slow skeletal troponin C. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0 mouse myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human Troponin C antibody, clone 1A2 recognizes human Troponin C, an 18kDa subunit of the Troponin complex found on actin filaments in muscle tissue. Troponin C (TnC) is responsible for binding calcium ions. In the absence of calcium, TnC has an inhibitory action on the actin filaments. When calcium binds to TnC, a conformational change takes place in Troponin I, which in turn causes a change in another associated protein, tropomyosin. Troponin and tropomyosin is repositioned away from the actin filaments, leaving the myosin binding sites available for cross-bridges to form and muscle contraction to occur. Mouse anti Human Troponin C antibody, clone 1A2 recognizes free cardiac Troponin C and TnC in binary complex with cardiac Troponin I. The antibody does not recognize free cardiac Troponin I or cardiac Troponin T.
ncbi gi num :
4507615
ncbi acc num :
NP_003271.1
ncbi gb acc num :
NM_003280.2
uniprot acc num :
P63316
ncbi mol weight :
18,403 Da
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Cardiac Muscle Contraction Pathway 93344!!Cardiac Muscle Contraction Pathway 93992!!Dilated Cardiomyopathy Pathway 121494!!Dilated Cardiomyopathy Pathway 121285!!Hypertrophic Cardiomyopathy (HCM) Pathway 114229!!Hypertrophic Cardiomyopathy (HCM) Pathway 106591
ncbi summary :
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
size :
0.2 mg
price :
400 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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