MyBioSource

antibody

MOUSE ANTI HUMAN LACTOFERRIN

MBS214508

0.2 mg

390 USD

monoclonal

mouse

human

western blot, enzyme immunoassay, ELISA

MBS214508

Antibody

MOUSE ANTI HUMAN LACTOFERRIN

LACTOFERRIN

lactotransferrin isoform 2; Lactotransferrin; lactotransferrin; epididymis luminal protein 110; growth-inhibiting protein 12; kaliocin-1; lactoferricin; lactoferroxin; neutrophil lactoferrin; talalactoferrin; lactotransferrin; Growth-inhibiting protein 12; TalalactoferrinCleaved into the following 5 chains:Lactoferricin-H; Lfcin-H; Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C

LTF; LTF; LF; HLF2; GIG12; HEL110; GIG12; LF; Lactoferrin; Lfcin-H

TRFL_HUMAN

Monoclonal

IgG1

1A1

Mouse

666

Purified. Purified IgG - liquid

Approximate Protein Concentration: 1.0mg/ml

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

ELISA (EIA), Western Blot (WB)

Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Purified Lactoferrin from human milk. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human

Mouse anti Human Lactoferrin antibody, clone 1A1 recognizes human lactoferrin, a 78kDa globular protein found in body secretions such as milk and saliva and is a member of the transferrin family proteins. Transferrins control the level of free iron in the body, by binding and transporting iron. Lactoferrin does not appear to have a transporting function, instead it has antimicrobial activity, by keeping the levels of iron in body fluids low and thus preventing microbes from acquiring iron. Removing free iron from body fluids and inflamed areas also serve to protect against the damaging effects of free radicals. Lactoferrin is used as a therapeutic and prophylactic treatment of various illnesses, such as cancers and intestinal illnesses.

312433998

NP_001186078.1

NM_001199149.1

P02788

73,161 Da

Amyloids Pathway 366238!!Disease Pathway 530764!!Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway 645267!!Mtb Iron Assimilation By Chelation Pathway 1127564!!Phagosomal Maturation (early Endosomal Stage) Pathway 645268!!Response Of Mtb To Phagocytosis Pathway 1127560

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

0.2 mg

390 USD