antibody

MOUSE ANTI HUMAN H-FABP

MBS214475

0.2 mg

365 USD

monoclonal

mouse

nonconjugated

1.00E+02

ELISA, enzyme immunoassay

Antibody

MOUSE ANTI HUMAN H-FABP

H-FABP

fatty acid-binding protein, heart; Fatty acid-binding protein, heart; fatty acid-binding protein, heart; Fatty acid-binding protein 3, muscle; fatty acid binding protein 11; heart-type fatty acid-binding protein; mammary-derived growth inhibitor; muscle fatty acid-binding protein; fatty acid binding protein 3, muscle and heart; Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; M-FABP

H-FABP

FABP3; FABP3; MDGI; FABP11; H-FABP; M-FABP; O-FABP; FABP11; MDGI; H-FABP; MDGI; M-FABP

FABPH_HUMAN

Monoclonal

IgG1

1.00E+02

Mouse

133

Purified. Purified IgG - liquid

IgG concentration 1.0mg/ml

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

ELISA (EIA), Immunoassay (IY)

Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Human heart FABP (H-FABP). Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human

Mouse anti Human H-FABP antibody, clone 10E1 detects human H-FABP, also known as heart type fatty-acid binding protein, and FABP3. H-FABP belongs to the FABP family, and is a 14kDa cytosolic non-enzymatic protein involved in the uptake, transport and metabolism of fatty acids. H-FABP also has a role in cell proliferation and is a candidate tumour suppressor gene in breast cancer. H-FABP was initially purified from the heart muscle, but has since been found to have a widespread tissue distribution, with highest concentration in cardiac and skeletal muscle. H-FABP has been implicated in neurodegenerative disorders, including Down syndrome and Alzheimer's disease, and is a specific and sensitive biomarker for acute myocardial infarctions.

4758328

NP_004093.1

NM_004102.3

P05413

14,858 Da

PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008]

0.2 mg

365 USD