catalog number :
MBS214468
products full name :
MOUSE ANTI EPSTEIN-BARR VIRUS NUCLEAR ANTIGEN
products short name :
EPSTEIN-BARR VIRUS NUCLEAR ANTIGEN
other names :
EBNA-1 protein; Epstein-Barr nuclear antigen 1; EBNA-1 protein
other gene names :
BKRF1; EBNA1; EBNA-1; EBV nuclear antigen 1
uniprot entry name :
EBNA1_EBVB9
specificity :
This item specifically recognises the repetitive Gly-Ala region of EBV (Epstein-Barr Virus) nuclear antigen 1 (EBNA-1), a viral protein expressed consistently by EBV- associated malignancies. Epstein-Barr Virus, also known as HHV-4 (Human herpesvirus 4), is a member of the herpesvirus family and one of the most common infectious viruses known, being responsible for a wide range of illnesses from infectious mononucleosis to nasal-pharyngeal cancer. EBNA-1 is the only viral protein expressed during group 1 latency and mediates the replication and partitioning of the episome during host cell division, binding to a replication origin (oriP) within the viral genome. The Gly-Ala repeat recognized by This item, inhibits the host's CD8-restricted cytotoxic T-cell response to infected cells, by impairing antigen processing and MHC class I-restricted antigen presentation. This item is reported as being suitable for use in immunocytochemistry.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Viral
products description :
MBS214468 specifically recognises the repetitive Gly-Ala region of EBV (Epstein-Barr Virus) nuclear antigen 1 (EBNA-1), a viral protein expressed consistently by EBV- associated malignancies. Epstein-Barr Virus, also known as HHV-4 (Human herpesvirus 4), is a member of the herpesvirus family and one of the most common infectious viruses known, being responsible for a wide range of illnesses from infectious mononucleosis to nasal-pharyngeal cancer. EBNA-1 is the only viral protein expressed during group 1 latency and mediates the replication and partitioning of the episome during host cell division, binding to a replication origin (oriP) within the viral genome. The Gly-Ala repeat recognized by MBS214468, inhibits the host's CD8-restricted cytotoxic T-cell response to infected cells, by impairing antigen processing and MHC class I-restricted antigen presentation. MBS214468 is reported as being suitable for use in immunocytochemistry.
ncbi acc num :
YP_401677.1
ncbi gb acc num :
NC_007605.1
ncbi mol weight :
56,427 Da