product summary
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company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MOUSE PLVAP
catalog :
MBS214383
quantity :
0.1 mg
price :
205 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MECA-32
reactivity :
mouse
application :
flow cytometry, FACS
more info or order :
product information
catalog number :
MBS214383
products type :
Antibody
products full name :
RAT ANTI MOUSE PLVAP
products short name :
PLVAP
other names :
plasmalemma vesicle-associated protein; Plasmalemma vesicle-associated protein; plasmalemma vesicle-associated protein; MECA-32 antigen; plasmalemma vesicle protein 1; plasmalemma vesicle associated protein; MECA-32 antigen; Plasmalemma vesicle protein 1; PV-1
products gene name :
PLVAP
other gene names :
Plvap; Plvap; Pv1; MECA32; Pv1; PV-1
uniprot entry name :
PLVAP_MOUSE
clonality :
Monoclonal
isotype :
IgG2a
clone :
MECA-32
host :
Rat
sequence length :
438
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Immunohistology - Frozen: Minimum Dilution: 1/25; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Fusion Partners: Spleen cells from immunised rat were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Rat anti Mouse PLVAP antibody, clone MECA-32 recognizes murine plasmalemma vesicle-associated protein (PLVAP), a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumour angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.
ncbi gi num :
255522953
ncbi acc num :
NP_115774.2
ncbi gb acc num :
NM_032398.2
uniprot acc num :
Q91VC4
ncbi mol weight :
49,933 Da
uniprot summary :
PLVAP: Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability. Protein type: Cell surface; Membrane protein, integral. Cellular Component: cell surface; membrane; cytoplasm; integral to membrane; plasma membrane; caveola; intracellular. Molecular Function: protein homodimerization activity. Biological Process: positive regulation of cellular extravasation; tumor necrosis factor-mediated signaling pathway; MAPKKK cascade
size1 :
0.1 mg
price1 :
205 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
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