MOUSE ANTI HUMAN FSH ALPHA:Biotin | MyBioSource MBS214244 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MOUSE ANTI HUMAN FSH ALPHA:Biotin

catalog :

MBS214244

quantity :

0.5 mg

price :

570 USD

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

[F1 (BGN/F62/01)]

reactivity :

human

application :

ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS214244

products type :

Antibody

products full name :

MOUSE ANTI HUMAN FSH ALPHA:Biotin

products short name :

[FSH]

other names :

[glycoprotein hormones alpha chain isoform 2; Glycoprotein hormones alpha chain; glycoprotein hormones alpha chain; FSH-alpha; LSH-alpha; TSH-alpha; anterior pituitary glycoprotein hormones common subunit alpha; choriogonadotropin alpha chain; chorionic gonadotrophin subunit alpha; chorionic gonadotropin, alpha polypeptide; follicle-stimulating hormone alpha chain; follicle-stimulating hormone alpha subunit; follitropin alpha chain; luteinizing hormone alpha chain; lutropin alpha chain; thyroid-stimulating hormone alpha chain; thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain]

products gene name :

[FSH ALPHA]

other gene names :

[CGA; CGA; HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA; CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha]

uniprot entry name :

GLHA_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

[F1 (BGN/F62/01)]

host :

Mouse

sequence length :

116

specificity :

Mouse anti Human FSH alpha antibody, clone F1 (BGN/F62/01) detects the alpha subunit of Follicle-stimulating hormone (FSH alpha). FSH is secreted by the pituitary, and is a member of the glycoprotein hormone family which includes Human chorionic gonadotropin (hCG), Luteinizing hormone (LH), and Thyroid stimulating hormone (TSH). These hormones are all structurally related and contain a common alpha subunit non-covalently bound to a hormone specific beta subunit, which determines receptor specificity. Both of the subunits are necessary for hormone action.

form :

Biotin. Purified IgG conjugated to Biotin - liquid

concentration :

Approximate Protein Concentration: 1.0mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

ELISA (EIA)

app notes :

ELISA: Minimum Dilution: 1/100; Maximum Dilution: 1/1000

other info1 :

Perservative Stabilisers: 0.09% Sodium Azide (NaN3). Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

other info2 :

Immunogen: Native. Buffer Solution: Phosphate buffered saline. Target Species: Human

products description :

ncbi gi num :

4502787

ncbi acc num :

NP_000726.1

ncbi gb acc num :

NM_000735.3

uniprot acc num :

P01215

ncbi mol weight :

13,075 Da

ncbi pathways :

Amine-derived Hormones Pathway (160983); Androgen Biosynthesis Pathway (106154); Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); FSH Signaling Pathway (672455); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548)

ncbi summary :

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

uniprot summary :

CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6q12-q21. Cellular Component: extracellular region. Molecular Function: protein binding; hormone activity. Biological Process: cellular protein metabolic process; cell-cell signaling; positive regulation of cell proliferation; peptide hormone processing; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration

size1 :

0.5 mg

price1 :

570 USD

more info or order :

MyBioSource product webpage