This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD338
catalog :
MBS214224
quantity :
1 ml
price :
1055 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
western blot
product information
catalog number :
MBS214224
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD338
products short name :
CD338
other names :
ATP-binding cassette sub-family G member 2 isoform 2; ATP-binding cassette sub-family G member 2; ATP-binding cassette sub-family G member 2; ABC transporter; ATP-binding cassette transporter G2; breast cancer resistance protein; mitoxantrone resistance-associated protein; multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2; placenta specific MDR protein; placenta-specific ATP-binding cassette transporter; urate exporter; ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group); Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; Urate exporter; CD_antigen: CD338
products gene name :
CD338
other gene names :
ABCG2; ABCG2; MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; CDw338; UAQTL1; EST157481; ABCP; BCRP; BCRP1; MXR
uniprot entry name :
ABCG2_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
BXP-21
host :
Mouse
sequence length :
611
specificity :
This item recognises an internal epitope of CD338, otherwise known as the Breast Cancer Resistance Protein (BCRP), a 70kDa transmembrane half transporter involved in multidrug resistance. This item does not cross react with human MDR1, MRP1 or MRP2 gene products.
form :
Serum free tissue Culture Supernatant - liquid
concentration :
IgG concentration 0.25 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Western Blot (WB)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3). 0.7% Bovine Serum Albumin
other info2 :
Immunogen: Fusion protein consisting of the E Coli maltose binding protein and a 126 amino acid part of the CD338 peptide corresponding to aa 271-396 of BCRP according to Genebank accession number AF103796. HPRD:04783 . Target Species: Human
products description :
MBS214224 recognises an internal epitope of CD338, otherwise known as the Breast Cancer Resistance Protein (BCRP), a 70kDa transmembrane half transporter involved in multidrug resistance. MBS214224 does not cross react with human MDR1, MRP1 or MRP2 gene products.
ncbi gi num :
383792176
ncbi acc num :
NP_001244315.1
ncbi gb acc num :
NM_001257386.1
uniprot acc num :
Q9UNQ0
ncbi mol weight :
70kDa
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!Abacavir Transmembrane Transport Pathway 645350!!Abacavir Transport And Metabolism Pathway 645349!!Bile Secretion Pathway 193146!!Bile Secretion Pathway 193095!!Fluoropyrimidine Activity Pathway 198778!!HIF-1-alpha Transcription Factor Network Pathway 138045!!HIF-2-alpha Transcription Factor Network Pathway 137956!!Irinotecan Pathway 198905
ncbi summary :
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
size :
1 ml
price :
1055 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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