This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MBP (aa82-87)
catalog :
MBS214142
quantity :
2 mL
price :
440 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
12
reactivity :
cow
application :
western blot, ELISA, immunocytochemistry, radioimmunoassay, enzyme immunoassay
product information
catalog number :
MBS214142
products type :
Antibody
products full name :
RAT ANTI MBP (aa82-87)
products short name :
MBP
other names :
Myelin basic protein; Myelin basic protein; myelin basic protein; 20 kDa microtubule-stabilizing protein; myelin A1 protein; myelin basic protein<; 20 kDa microtubule-stabilizing protein; Myelin A1 protein
products gene name :
MBP
other gene names :
MBP; MBP; MBP
uniprot entry name :
MBP_BOVIN
clonality :
Monoclonal
isotype :
IgG2a
clone :
12
host :
Rat
sequence length :
169
form :
Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Immunofluorescence (IF), Radioimmunoassays (RIA), Western Blot (WB)
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide
other info2 :
Buffer Solution: 0.1M TRIS. Target Species: Bovine
products description :
Rat anti MBP antibody, clone 12 recognizes myelin basic protein from a wide range of species. The antibody reacts weakly with peptides ending in the Phe 91 where the 91-92 Phe-Phe bond is broken. Synthetic peptide 82-99 reacts very well, as does intact MBP. Further epitope analysis indicates binding to a region defined by amino acids 82-87 (DENPVV). Clone 12 has been reported as being suitable for use in Western blotting.
ncbi gi num :
126796
ncbi acc num :
P02687.1
uniprot acc num :
P02687
ncbi mol weight :
18,323 Da
ncbi pathways :
MAPK Cascade Pathway (920927)
uniprot summary :
MBP: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. Homodimer. Isoform 3 exists as a homodimer. MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system. Belongs to the myelin basic protein family. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Cytoskeletal. Cellular Component: plasma membrane; myelin sheath. Molecular Function: protein binding; structural constituent of myelin sheath
size1 :
2 mL
price1 :
440 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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