catalog number :
MBS214099
products full name :
MOUSE ANTI EPSTEIN-BARR VIRUS LMP
products short name :
EPSTEIN-BARR VIRUS LMP
other names :
LMP1; Latent membrane protein 1; LMP1; hypothetical protein; Protein p63Protein p25
other gene names :
LMP1; LMP1; LMP-1
uniprot entry name :
LMP1_EBVB9
form :
Tissue Culture Supernatant - lyophilised
storage stability :
Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
tested application :
Immunohistology Frozen, Immunohistology Paraffin*
app notes :
Immunohistology - Frozen: Minimum Dilution: 1/100; Maximum Dilution: 1/200;. Immunohistology - Paraffin: Minimum Dilution: 1/100; Maximum Dilution: 1/200; Application Note: This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.
other info1 :
Reconstitution: Reconstitute with 1.0 ml distilled water. Perservative Stabilisers: 15mM Sodium Azide
other info2 :
Immunogen: Recombinant fusion protein of bacterial beta-galactosidase and EBV LMP-1. Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse X63-Ag8.653 myeloma cell line. Target Species: Viral
products description :
Mouse anti Epstein-Barr Virus LMP antibody, clone CS1/CS2/CS3/CS4 is a cocktail of 4 antibodies recognising different epitopes of Epstein Barr Virus Latent Membrane Protein (LMP). Mouse anti Epstein-Barr Virus LMP antibody, clone CS1/CS2/CS3/CS4 stains EBV positive lymphoblastoid cell lines and EBV infected B cells in infectious mononucleosis.
ncbi acc num :
YP_401722.1
ncbi gb acc num :
NC_007605.1
ncbi mol weight :
41,982 Da
uniprot summary :
LMP1: Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. It is a short-lived protein probably degraded by the proteasome