This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI PROTEIN KINASE C ALPHA
catalog :
MBS214027
quantity :
2 ml
price :
405 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
133
reactivity :
human
application :
western blot
product information
catalog number :
MBS214027
products type :
Antibody
products full name :
MOUSE ANTI PROTEIN KINASE C ALPHA
products short name :
PROTEIN KINASE C ALPHA
other names :
protein kinase C alpha type; Protein kinase C alpha type; protein kinase C alpha type; PKC-A; aging-associated gene 6; protein kinase C, alpha
other gene names :
PRKCA; PRKCA; AAG6; PKCA; PRKACA; PKC-alpha; PKCA; PRKACA; PKC-A; PKC-alpha
uniprot entry name :
KPCA_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
133
host :
Mouse
reactivity :
Mammals
sequence length :
672
form :
Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C for one month or at -20 degree C for longer. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Western Blot (WB)
app notes :
Immunohistology - Frozen: Minimum Dilution: Neat; Maximum Dilution: 1/10;. Western Blotting: Minimum Dilution: 1/10; Maximum Dilution: 1/500
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide
products description :
Mouse anti Protein Kinase C alpha antibody, clone 133 recognizes the alpha isoform of protein kinase C. PKC-alpha is a 672 amino acid enzyme containng a single AGC-kinase C-terminal domain, a C2 domain, 2 phorbol-ester/DAGtype zinc fingers and a single protein kinase domain (UniProt: P17252). Mouse anti Protein Kinase C alpha antibody, clone 133 recognizes the sequence PQFVHPILQSAV at the C terminus of PKCalpha.
ncbi gi num :
4506067
ncbi acc num :
NP_002728.1
ncbi gb acc num :
NM_002737.2
uniprot acc num :
P17252
ncbi mol weight :
76,750 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!ATF-2 Transcription Factor Network Pathway 138006!!Acetylcholine Regulates Insulin Secretion Pathway 105924!!Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Aldosterone-regulated Sodium Reabsorption Pathway 130626!!Aldosterone-regulated Sodium Reabsorption Pathway 130590!!Alpha6-Beta4 Integrin Signaling Pathway 198807
ncbi summary :
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
size :
2 ml
price :
405 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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