This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN Grb2
catalog :
MBS213986
quantity :
2 ml
price :
415 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
immunoprecipitation
product information
catalog number :
MBS213986
products type :
Antibody
products full name :
MOUSE ANTI HUMAN Grb2
products short name :
Grb2
other names :
growth factor receptor-bound protein 2 isoform 1; Growth factor receptor-bound protein 2; growth factor receptor-bound protein 2; HT027; SH2/SH3 adapter GRB2; abundant SRC homology; epidermal growth factor receptor-binding protein GRB2; growth factor receptor-bound protein 3; protein Ash; growth factor receptor-bound protein 2; Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2
products gene name :
Grb2
other gene names :
GRB2; GRB2; ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2; ASH
uniprot entry name :
GRB2_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
R13
host :
Mouse
sequence length :
217
form :
Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunoprecipitation (IP)
other info1 :
Perservative Stabilisers: 0.02% Sodium Azide
other info2 :
Target Species: Human
products description :
Mouse anti Human Grb2 antibody, clone R13 recognizes human Growth factor receptor-bound protein 2, also known as Grb2, SH2/SH3 adapter GRB2 or Protein Ash. Grb2 is a 217 amino acid adapter protein linking cell surface growth factor receptors and the Ras signaling pathway. Grb2 contains a single SH2 domain and two SH3 domains. Studies on murine Grb2 indicate an essential role during embryogenesis and in malignant transformation (Cheng et al. 1998).
ncbi gi num :
4504111
ncbi acc num :
NP_002077.1
ncbi gb acc num :
NM_002086.4
uniprot acc num :
P62993
ncbi mol weight :
20,557 Da
ncbi pathways :
Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adaptive Immune System Pathway 366160!!Alcoholism Pathway 585563!!Alcoholism Pathway 587116!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Angiopoietin Receptor Tie2-mediated Signaling Pathway 137917!!Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway 576249!!Axon Guidance Pathway 105688!!B Cell Receptor Signaling Pathway 198909
ncbi summary :
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
size :
2 ml
price :
415 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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