catalog number :
MBS213983
products full name :
MOUSE ANTI PI-3 KINASE p85 SUBUNIT ALPHA
products short name :
PI-3 KINASE p85 SUBUNIT ALPHA
other names :
phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase p85 subunit alpha; PI3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PI3K regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha); phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); ptdIns-3-kinase p85-alpha; ptdIns-3-kinase regulatory subunit alpha; ptdIns-3-kinase regulatory subunit p85-alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
other gene names :
PIK3R1; PIK3R1; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
uniprot entry name :
P85A_BOVIN
reactivity :
Human, Monkey, Mouse, Rat
form :
Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunoprecipitation (IP), Western Blot (WB)
app notes :
Immunoprecipitation: Maximum Dilution: Neat;. Western Blotting: Maximum Dilution: 1/200
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Tissue Culture Supernatant containing 0.2M Tris/HCl pH7.4 and 5-10% foetal calf serum
other info2 :
Target Species: Bovine
products description :
Mouse anti PI-3 Kinase p85 Subunit alpha antibody, clone U13 recognizes the SH3 domain of the p85 alpha subunit of bovine PI3 kinase, also known as Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha or PtdIns-3-kinase regulatory subunit p85-alpha. p85 alpha PI3 kinase is a 724 amino acid ~85kDa protein bearing a single Rho-GAP domain, two SH2 domains and a single N-terminal SH3 domain. Multiple isoforms of the protein can be generated by alternative splicing, mouse anti PI-3 Kinase p85 subunit alpha antibody, clone U13 recognizes only those isoforms containing the SH3 domain (isoforms 1 and 4) but not those lacking the domain (isoforms 2,3 and 5). Deficiencies in the expression of the PIK3R1 gene can lead to immunodeficiency Agammaglobulinemia 7, autosomal recessive, diue to the inhibition of B cell development (Conley et al. 2012) and the develpmental condition SHORT syndrome (Chudasama et al. 2013).
ncbi acc num :
NP_777000.1
ncbi gb acc num :
NM_174575.1
ncbi mol weight :
83,497 Da
ncbi pathways :
AMPK Signaling Pathway (989258); AMPK Signaling Pathway (992181); Acute Myeloid Leukemia Pathway (84352); Acute Myeloid Leukemia Pathway (529); Adaptive Immune System Pathway (1119287); Adrenergic Signaling In Cardiomyocytes Pathway (908260); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Aldosterone-regulated Sodium Reabsorption Pathway (130625); Aldosterone-regulated Sodium Reabsorption Pathway (130590); Alpha6-Beta4 Integrin Signaling Pathway (920929)