product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CATHEPSIN D
catalog :
MBS213942
quantity :
0.2 ml
price :
490 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS213942
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CATHEPSIN D
products short name :
CATHEPSIN D
other names :
cathepsin D preproprotein; Cathepsin D; cathepsin D; ceroid-lipofuscinosis, neuronal 10; epididymis secretory sperm binding protein Li 130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease; cathepsin D; N/A
other gene names :
CTSD; CTSD; CPSD; CLN10; HEL-S-130P; CPSD
uniprot entry name :
CATD_HUMAN
clonality :
Monoclonal
isotype :
IgG2b
clone :
C5
host :
Mouse
sequence length :
412
specificity :
This item recognises human Cathepsin D, a lysosomal protease found in very low concentrations in normal cells. Cathepsin D is secreted as a precursor protein, but it is processed in the cell to produce the mature form.
form :
Ig fraction - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Immunohistology Paraffin
app notes :
Immunohistology: Trypsinisation may be required. Immunohistology - Paraffin: Minimum Dilution: 1/50; Maximum Dilution: 1/200
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
other info2 :
Immunogen: Cathepsin D purified from human spleen. Histology Positive Control Tissue: Liver. Fusion Partners: Spleen cells from immunised mice were fused with cells of the p3-NS1-Ag4-1 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
MBS213942 recognises human Cathepsin D, a lysosomal protease found in very low concentrations in normal cells. Cathepsin D is secreted as a precursor protein, but it is processed in the cell to produce the mature form.
ncbi gi num :
4503143
ncbi acc num :
NP_001900.1
ncbi gb acc num :
NM_001909.4
uniprot acc num :
P07339
ncbi mol weight :
44,552 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Ceramide Signaling Pathway 138023!!Collagen Degradation Pathway 730309!!Degradation Of The Extracellular Matrix Pathway 576263!!Direct P53 Effectors Pathway 137939!!Extracellular Matrix Organization Pathway 576262!!Immune System Pathway 106386!!LKB1 Signaling Events Pathway 137957!!Lysosome Pathway 99052!!Lysosome Pathway 96865
ncbi summary :
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq, Jul 2008]
size :
0.2 ml
price :
490 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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