product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MOUSE Gr-1:RPE
catalog :
MBS213804
quantity :
100 Tests
price :
230 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
application :
FACS, flow cytometry
more info or order :
product information
catalog number :
MBS213804
products type :
Antibody
products full name :
RAT ANTI MOUSE Gr-1:RPE
products short name :
Gr-1
other names :
Lymphocyte antigen 6G; Lymphocyte antigen 6G; Ly-6G.1
products gene name :
Gr-1
other gene names :
Ly6g; Ly-6G
uniprot entry name :
LY6G_MOUSE
clonality :
Monoclonal
isotype :
IgG2b
clone :
RB6-8C5
host :
Rat
sequence length :
111
form :
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
storage stability :
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/5
other info1 :
Reconstitution: Reconstitute with 1 ml distilled water. Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. 5% Sucrose. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Rat anti Mouse Gr-1 antibody, clone RB6-8C5 recognizes the mouse Gr-1 antigen, a 21 -25kDa GPI anchored cell surface protein bearing a single uPAR/Ly6 domain that belongs to the Ly-6 family of proteins (Lee et al. 2013). Rat anti Mouse Gr-1 antibody, clone RB6-8C5 reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been reported (Fleming et al. 1993). However, other observations dispute the cross-reactivity of clone RB6-8C5 with the Ly-6C protein with the alternative explanation that certain sub-populations of bone marrow cells simultaneously express both Ly-6C and Ly-6G (Nagendra et al. 2007) The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Rat anti Mouse Gr-1 antibody, clone RB6-8C5 has been used successfully for the depletion of mature neutrophils in vivo (Czuprynski, C.J. et al 1994, Daley et al. 2008).
ncbi gi num :
547876
ncbi acc num :
P35461.1
uniprot acc num :
P35461
ncbi mol weight :
11,798 Da
size :
100 Tests
price :
230 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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