catalog number :
MBS213771
products full name :
MOUSE ANTI RAT CD88:RPE
products short name :
CD88
other names :
C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor 1; C5a-R; C5aR; complement C5a receptor; complement component 5, receptor 1; complement component 5a receptor 1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen: CD88
products gene name :
CD88
other gene names :
C5ar1; C5ar1; C5r1; C5r1; C5a-R; C5aR
uniprot entry name :
C5AR1_RAT
form :
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
storage stability :
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of reconstitution.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul . Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/5
other info1 :
Reconstitution: Reconstitute with 1 ml distilled water. Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. 5% Sucrose. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Transfectants expressing rat CD88. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse Ag8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Rat
products description :
Mouse anti Rat CD88 antibody, clone R63 recognizes the rat CD88 cell surface receptor, also known as C5aR, which functions as a receptor for the C5a fragment of the complement factor C5. CD88 is expressed by cells of the myeloid lineage such as monocytes and macrophages.
ncbi acc num :
NP_446071.1
ncbi gb acc num :
NM_053619.1
ncbi mol weight :
39,417 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 1120714!!Complement And Coagulation Cascades Pathway 198461!!Complement And Coagulation Cascades Pathway 83465!!Complement And Coagulation Cascades Pathway 484!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1122016!!Disease Pathway 1121849!!G Alpha (i) Signalling Events Pathway 1120745!!GPCR Downstream Signaling Pathway 1120743!!GPCR Ligand Binding Pathway 1120713!!Metabolic Disorders Of Biological Oxidation Enzymes Pathway 1121989
ncbi summary :
binds complement component 5 and induces Ca+2 release from intracellular stores [RGD, Feb 2006]