product summary
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company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD177:RPE
catalog :
MBS213707
quantity :
100 Tests
price :
445 USD
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
MEM-166
reactivity :
human
application :
flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS213707
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD177:RPE
products short name :
CD177
other names :
CD177 antigen; CD177 antigen; CD177 antigen; NB1 glycoprotein; cell surface receptor; human neutrophil alloantigen 2a; polycythemia rubra vera protein 1; CD177 molecule; Human neutrophil alloantigen 2a; HNA-2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1; CD_antigen: CD177
products gene name :
CD177
other gene names :
CD177; CD177; NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP; NB1; PRV1; HNA-2a; NB1 GP; PRV-1
uniprot entry name :
CD177_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
MEM-166
host :
Mouse
sequence length :
145
form :
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised.
storage stability :
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Maximum Dilution: Neat
other info1 :
Reconstitution: Reconstitute with 1 ml distilled water. Perservative Stabilisers: 0.09% Sodium Azide. 1.0% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G.
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD177 antibody, clone MEM-166 recognizes human CD177 (neutrophil glycoprotein NB1). The neutrophil NB1 antigen is expressed by 97% of the caucasian population. Antibodies against NB1 can be involved in neonatal alloimmune neutropenia (NAN).
ncbi gi num :
110735433
ncbi acc num :
NP_065139.2
ncbi gb acc num :
NM_020406.3
uniprot acc num :
Q8N6Q3
ncbi mol weight :
15,683 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (106062); Common Pathway (106060); Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028)
ncbi summary :
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
uniprot summary :
CD177: Induced by CSF3 in resting granulocytes. Induced in patients with polycythemia vera (PV) and with essential thrombocythemia (ET). 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: plasma membrane. Biological Process: blood coagulation; leukocyte migration
size1 :
100 Tests
price1 :
445 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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