catalog number :
MBS213570
products full name :
MOUSE ANTI HUMAN CD4:RPE
products short name :
CD4
other names :
T-cell surface glycoprotein CD4 isoform 1; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 antigen (p55); CD4 receptor; T-cell surface antigen T4/Leu-3; CD4 molecule; T-cell surface antigen T4/Leu-3; CD_antigen: CD4
other gene names :
CD4; CD4; CD4mut; N/A
uniprot entry name :
CD4_HUMAN
form :
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
storage stability :
Prior to reconstitution store at 4 degree C. Following reconstitution store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood . Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
other info1 :
Reconstitution: Reconstitute with 1 ml distilled water. Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. 5% Sucrose. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
ncbi acc num :
NP_000607.1
ncbi gb acc num :
NM_000616.4
ncbi mol weight :
51,111 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Alpha-defensins Pathway 530758!!Antigen Processing And Presentation Pathway 83074!!Antigen Processing And Presentation Pathway 485!!Arf1 Pathway 137927!!Binding And Entry Of HIV Virion Pathway 105986!!C-MYB Transcription Factor Network Pathway 138073!!CXCR4-mediated Signaling Events Pathway 137910!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480
ncbi summary :
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]