catalog number :
MBS213193
products full name :
MOUSE ANTI HUMAN CD90
products short name :
CD90
other names :
thy-1 membrane glycoprotein preproprotein; Thy-1 membrane glycoprotein; thy-1 membrane glycoprotein; CDw90; Thy-1 T-cell antigen; thy-1 antigen; Thy-1 cell surface antigen; CDw90; Thy-1 antigen; CD_antigen: CD90
products gene name :
CD90
other gene names :
THY1; THY1; CD90
uniprot entry name :
THY1_HUMAN
reactivity :
Cynomolgus monkey
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen*, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Immunohistology - Frozen: Application Note: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. MyBioSource recommends the use of acetone fixation for frozen sections. . Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/50
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by ion exchange chromatography
other info2 :
Histology Positive Control Tissue: Human Brain, thymus. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD90 antibody, clone F15-42-1 recognizes the human CD90 cell surface antigen, a 25kD glycoprotein homologous to rat Thy1. The antigen is expressed by a subset of CD34+ve cells in the bone marrow and by prothymocytes within the thymus. CD90 is also expressed extensively within the brain. Mouse anti Human CD90 antibody, clone F15-42-1 is routinely tested in flow cytometry on the MOLT4 cell line.
ncbi acc num :
NP_006279.2
ncbi gb acc num :
NM_006288.3
ncbi mol weight :
17,935 Da
ncbi pathways :
Cardiac Progenitor Differentiation Pathway (712094); IL4-mediated Signaling Events Pathway (137933); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Amb2 Integrin Signaling Pathway (137945)
ncbi summary :
This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
uniprot summary :
THY1: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Protein type: Membrane protein, GPI anchor; Cell adhesion; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 11q23.3. Cellular Component: anchored to external side of plasma membrane; growth cone; focal adhesion; endoplasmic reticulum; integral to plasma membrane; dendrite; apical plasma membrane; plasma membrane; cytosol; lipid raft; external side of plasma membrane. Molecular Function: integrin binding; protein binding; protein kinase binding. Biological Process: focal adhesion formation; negative regulation of T cell receptor signaling pathway; cytoskeleton organization and biogenesis; T cell receptor signaling pathway; cell-cell adhesion; retinal cone cell development; negative regulation of protein kinase activity; negative regulation of axonogenesis; positive regulation of T cell activation; positive regulation of release of sequestered calcium ion into cytosol; angiogenesis; negative regulation of cell migration; positive regulation of GTPase activity