catalog number :
MBS213145
products full name :
MOUSE ANTI HUMAN CD27
products short name :
CD27
other names :
CD27 antigen; CD27 antigen; CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; CD27 molecule; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD_antigen: CD27
products gene name :
CD27
other gene names :
CD27; CD27; T14; S152; Tp55; TNFRSF7; S152. LPFS2; TNFRSF7
uniprot entry name :
CD27_HUMAN
reactivity :
Cynomolgus monkey, Rhesus Monkey, Sheep
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 40 ug/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS), Immunoprecipitation (IP)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by ion exchange chromatography
other info2 :
Immunogen: Normal human blood lymphocytes. Fusion Partners: Spleen cells from immunised mice were fused with cells of the P3. X 63-Ag8-653 mouse myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti human CD27, clone LT27, recognizes the human T-cell activation antigen, CD27. This antigen is expressed on activated T lymphocytes and belongs to a family of proteins associated with the nerve growth factor receptor. CD27 is expressed by thymocytes and peripheral T cells and also by EBV transformed B cell lines. Mouse anti human CD27, clone LT27 precipitates a 55kDa protein under reducing conditions or a 120kDa protein under non-reducing conditions.
ncbi acc num :
NP_001233.1
ncbi gb acc num :
NM_001242.4
ncbi mol weight :
29,137 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]