product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD42b
catalog :
MBS213137
quantity :
0.2 mg
price :
415 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
immunoprecipitation, ELISA, FACS, flow cytometry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS213137
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD42b
products short name :
CD42b
other names :
platelet glycoprotein Ib alpha chain; Platelet glycoprotein Ib alpha chain; platelet glycoprotein Ib alpha chain; GP-Ib alpha; antigen CD42b-alpha; platelet membrane glycoprotein 1b-alpha subunit; glycoprotein Ib (platelet), alpha polypeptide; Antigen CD42b-alpha; CD_antigen: CD42bGlycocalicin
products gene name :
CD42b
other gene names :
GP1BA; GP1BA; BSS; GP1B; VWDP; CD42B; GPIbA; BDPLT1; BDPLT3; DBPLT3; CD42b-alpha; GP-Ib alpha; GPIb-alpha; GPIbA; Glycoprotein Ibalpha
uniprot entry name :
GP1BA_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
AK2
host :
Mouse
sequence length :
652
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Flow cytometry (FC/FACS), Immunoprecipitation (IP)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 100ul whole blood. Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD42b antibody, clone AK2 recognizes the human CD42b cell surface antigen, also known as platelet glycoprotein GP1B. CD42b is expressed by platelets and megakaryocytes. Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets
ncbi gi num :
291190772
ncbi acc num :
NP_000164.5
ncbi gb acc num :
NM_000173.6
uniprot acc num :
P07359
ncbi mol weight :
71,540 Da
ncbi pathways :
ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Formation Of Fibrin Clot (Clotting Cascade) Pathway 106057!!GP1b-IX-V Activation Signalling Pathway 187205!!Hematopoietic Cell Lineage Pathway 83078!!Hematopoietic Cell Lineage Pathway 489!!Hemostasis Pathway 106028!!Intrinsic Pathway 106059!!Platelet Adhesion To Exposed Collagen Pathway 106030!!Platelet Aggregation (Plug Formation) Pathway 106053
ncbi summary :
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. [provided by RefSeq, Oct 2013]
size :
0.2 mg
price :
415 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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