product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD41
catalog :
MBS213025
quantity :
0.1 mg
price :
230 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
FACS, flow cytometry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS213025
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD41
products short name :
CD41
other names :
integrin alpha-IIb preproprotein; Integrin alpha-IIb; integrin alpha-IIb; GPalpha IIb; platelet fibrinogen receptor, alpha subunit; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; protein phosphatase 1, regulatory subunit 93; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD_antigen: CD41Cleaved into the following 3 chains:Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2
products gene name :
CD41
other gene names :
ITGA2B; ITGA2B; GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93; GP2B; ITGAB; GPIIb
uniprot entry name :
ITA2B_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
PM6/248
host :
Mouse
sequence length :
1039
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Human platelet plasma membrane. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD41 antibody, clone PM6/248 recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.
ncbi gi num :
88758615
ncbi acc num :
NP_000410.2
ncbi gb acc num :
NM_000419.3
uniprot acc num :
P08514
ncbi mol weight :
103,218 Da
ncbi pathways :
Arf6 Signaling Events Pathway 138034!!Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Axon Guidance Pathway 105688!!Developmental Biology Pathway 477129!!Dilated Cardiomyopathy Pathway 121494!!Dilated Cardiomyopathy Pathway 121285!!ECM Proteoglycans Pathway 833812!!ECM-receptor Interaction Pathway 83068
ncbi summary :
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
230 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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