catalog number :
MBS212863
products full name :
MOUSE ANTI HUMAN IgG
products short name :
IgG
other names :
Ig gamma-3 chain C region; Ig gamma-3 chain C region; immunoglobulin heavy constant gamma 3 (G3m marker); HDC; Heavy chain disease protein
other gene names :
IGHG3; IGHG3; IgG3
uniprot entry name :
IGHG3_HUMAN
specificity :
This item recognises the Fc region of human immunoglobulin gamma chains. This antibody also cross-reacts strongly with rabbit IgG.
form :
Purified. Purified
concentration :
IgG concentration 1mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein A
other info2 :
Buffer Solution: Tris buffered saline. Target Species: Human
products description :
MBS212863 recognises the Fc region of human immunoglobulin gamma chains. This antibody also cross-reacts strongly with rabbit IgG.
ncbi mol weight :
41,287 Da
ncbi pathways :
Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); FCGR Activation Pathway (771578); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); IL4-mediated Signaling Events Pathway (137933); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway (771579)
uniprot summary :
IGHG3: Dimer linked by 12 disulfide bonds; it has an extra interchain disulfide bond at position 7 in addition to the 11 normally present in the hinge region. Chromosomal Location of Human Ortholog: 14q32.33. Cellular Component: extracellular space; extracellular region. Molecular Function: antigen binding. Biological Process: retinal homeostasis; innate immune response; complement activation, classical pathway; complement activation