product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI CHICKEN INTERFERON ALPHA
catalog :
MBS212785
quantity :
0.5 mg
price :
550 USD
clonality :
monoclonal
host :
mouse
reactivity :
chicken
application :
western blot, enzyme immunoassay, ELISA
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS212785
products type :
Antibody
products full name :
MOUSE ANTI CHICKEN INTERFERON ALPHA
products short name :
IFN ALPHA
other names :
interferon type A1/A2; Interferon type A1/A2; interferon type A1/A2; IFN alpha; interferon alpha; interferon type A3; interferon-alpha; interferon; N/A
other gene names :
IFNA3; IFNA1; IFNA; IFNA1; IFNA2; IFNA6; IFN-alpha; IFN-gamma; N/A
uniprot entry name :
IFNA1_CHICK
clonality :
Monoclonal
isotype :
IgG1
clone :
UMCh3-IFNa
host :
Mouse
sequence length :
193
specificity :
This item recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. This item does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 0.5 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: This item detects a band of approximately 19 kDa.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Recombinant chicken Interferon alpha. Buffer Solution: Phosphate buffered saline. Target Species: Chicken
products description :
MBS212785 recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. MBS212785 does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.
ncbi gi num :
45382199
ncbi acc num :
NP_990758.1
ncbi gb acc num :
NM_205427.1
uniprot acc num :
P42165
ncbi mol weight :
22,116 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 119307!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytosolic DNA-sensing Pathway 125152!!Cytosolic DNA-sensing Pathway 124833!!Herpes Simplex Infection Pathway 377875!!Herpes Simplex Infection Pathway 377865!!Influenza A Pathway 217175!!Influenza A Pathway 217150!!Jak-STAT Signaling Pathway 83972!!Jak-STAT Signaling Pathway 488
size :
0.5 mg
price :
550 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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