product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
HAMSTER ANTI MOUSE CD121a
catalog :
MBS212728
quantity :
0.25 mg
price :
365 USD
clonality :
monoclonal
host :
hamsters
reactivity :
mouse
application :
flow cytometry, immunoprecipitation, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS212728
products type :
Antibody
products full name :
HAMSTER ANTI MOUSE CD121a
products short name :
CD121a
other names :
interleukin-1 receptor type 1 isoform 1; Interleukin-1 receptor type 1; interleukin-1 receptor type 1; CD121 antigen-like family member A; IL-1 receptor alpha chain; IL-1R-1; IL-1R-alpha; IL-1RT-1; IL-1RT1; interleukin-1 receptor alpha; interleukin-1 receptor type I; p80; interleukin 1 receptor, type I; CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; Interleukin-1 receptor type I; p80; CD_antigen: CD121aCleaved into the following 2 chains:Interleukin-1 receptor type 1, membrane form; mIL-1R1; mIL-1RI; Interleukin-1 receptor type 1, soluble form; sIL-1R1; sIL-1RI
products gene name :
CD121a
other gene names :
Il1r1; Il1r1; IL-iR; CD121a; CD121b; IL-1R1; Il1r-1; Il-1r1; Il1ra; IL-1R-1; IL-1RT-1; IL-1RT1; IL-1R-alpha; mIL-1R1; mIL-1RI; sIL-1R1; sIL-1RI
uniprot entry name :
IL1R1_MOUSE
clonality :
Monoclonal
isotype :
IgG
clone :
JAMA-147
host :
Hamster
sequence length :
576
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS), Immunoprecipitation (IP)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Hamster anti Mouse CD121a monoclonal antibody, clone JAMA-147 recognizes murine CD121a, the ~80kDa type I interleukin-1 receptor. CD121a is a single pass type I membrane glycoprotein, weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a. Hamster anti mouse CD121 antibody, clone JAMA-147 has been reported to block IL-1 dependent cellular responses (Rogers et al. 1992).
ncbi gi num :
6680417
ncbi acc num :
NP_032388.1
ncbi gb acc num :
NM_008362.2
uniprot acc num :
P13504
ncbi mol weight :
66,698 Da
ncbi pathways :
Amoebiasis Pathway 167330!!Amoebiasis Pathway 167191!!Apoptosis Pathway 83257!!Apoptosis Pathway 470!!Apoptosis Signaling Pathway 522973!!Cytokine Signaling In Immune System Pathway 1110778!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!HTLV-I Infection Pathway 373903!!HTLV-I Infection Pathway 373889
size :
0.25 mg
price :
365 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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