product summary
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company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MOUSE CD150
catalog :
MBS212638
quantity :
0.1 mg
price :
210 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
9D1
reactivity :
mouse
application :
flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS212638
products type :
Antibody
products full name :
RAT ANTI MOUSE CD150
products short name :
CD150
other names :
signaling lymphocytic activation molecule; Signaling lymphocytic activation molecule; signaling lymphocytic activation molecule; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule family member 1; CD_antigen: CD150
products gene name :
CD150
other gene names :
Slamf1; Slamf1; Slam; CD150; IPO-3; CDw150; ESTM51; AA177906; 4933415F16; Slam
uniprot entry name :
SLAF1_MOUSE
clonality :
Monoclonal
isotype :
IgG1
clone :
9D1
host :
Rat
sequence length :
343
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: CHO cells stably transfected with mouse CD150. Fusion Partners: Spleen cells from immunised rats were fused with cells of a myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Rat anti Mouse CD150 antibody, clone 9D1 recognizes murine CD150, also known as signalling lymphocyte activation molecule (SLAM). Murine CD150 is a 75kDa cell surface glycoprotein that is expressed on T-cells and B-cells, and has been shown to be upregulated on activated T-cells and stimulated macrophages. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T-cells and B-cells. Rat anti Mouse CD150 antibody, clone 9D1 is reported to have functional activity (Howie et al. 2002).
ncbi gi num :
29336066
ncbi acc num :
NP_038758.2
ncbi gb acc num :
NM_013730.4
uniprot acc num :
Q9QUM4
ncbi mol weight :
36,590 Da
ncbi pathways :
Measles Pathway (213308); Measles Pathway (213277); XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway (755427)
uniprot summary :
SLAM: a type I membrane protein present on the surface of B cells, T cells and CD83+ dendritic cells. A high-affinity self-ligand considered to be important in bidirectional T B-cell stimulation. SLAM-induced signal-transduction events in T lymphocytes are different from those in B cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A (SAP) acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (SHP-2)-dependent signal transduction operates. Its cytoplasmic domain interacts with SAP through part of its SH2 domain, and with SHP-2. Three alternatively spliced isoforms have been described. Protein type: Receptor, misc.; Membrane protein, integral. Cellular Component: cell surface; membrane; plasma membrane; integral to membrane; phagocytic vesicle; external side of plasma membrane. Molecular Function: protein binding; receptor activity. Biological Process: regulation of catalytic activity; regulation of vesicle fusion; lymphocyte activation
size1 :
0.1 mg
price1 :
210 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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