catalog number :
MBS212563
products full name :
SHEEP ANTI HUMAN EGF RECEPTOR
products short name :
EGF R
other names :
epidermal growth factor receptor isoform a; Epidermal growth factor receptor; epidermal growth factor receptor; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; erb-b2 receptor tyrosine kinase 1; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
other gene names :
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; ERBB; ERBB1; HER1
uniprot entry name :
EGFR_HUMAN
specificity :
This item is a sheep monoclonal antibody specific for the human EGF receptor. This antibody may be of value in developing assays for EGF R in a range of biological samples.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul . Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/50
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
MBS212563 is a sheep monoclonal antibody specific for the human EGF receptor. This antibody may be of value in developing assays for EGF R in a range of biological samples.
ncbi acc num :
NP_005219.2
ncbi gb acc num :
NM_005228.3
ncbi mol weight :
69,228 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!Adaptive Immune System Pathway 366160!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!AhR Pathway 755436!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Androgen Receptor Signaling Pathway 198806!!Arf6 Signaling Events Pathway 138034!!Axon Guidance Pathway 105688!!Bladder Cancer Pathway 83115
ncbi summary :
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]