This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MOUSE CD180
catalog :
MBS212524
quantity :
0.25 mg
price :
755 USD
clonality :
monoclonal
host :
rat
reactivity :
mouse
application :
western blot, immunoprecipitation, flow cytometry, FACS
product information
catalog number :
MBS212524
products type :
Antibody
products full name :
RAT ANTI MOUSE CD180
products short name :
CD180
other names :
CD180 antigen; CD180 antigen; CD180 antigen; ly-78; lymphocyte antigen 78; radioprotective 105 kDa protein; CD180 antigen; Lymphocyte antigen 78; Ly-78; Radioprotective 105 kDa protein; CD_antigen: CD180
products gene name :
CD180
other gene names :
Cd180; Cd180; Ly78; RP105; F630107B15; Ly78; Rp105; Ly-78
uniprot entry name :
CD180_MOUSE
clonality :
Monoclonal
isotype :
IgG2a
clone :
RP/14
host :
Rat
sequence length :
661
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 0.5 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)*, Functional Assays (FN)*, Immunoprecipitation (IP), Western Blot (WB)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Application Note: CD180 is expressed at the cell surface in association with MD-1. CD180 may also be found free within the cell. For detection of intracellular CD180, MyBioSource recommends the use of Leucoperm prior to staining. . Functional Assays: Application Note: This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Rat anti Mouse CD180 antibody, clone RP/14  recognizes mouse CD180, also known as Lymphocyte antigen 78 or Radioprotective 105 kDa protein encoded by the RP105 gene. Mouse CD180 is a 661 amino acid ~105kDa single pass type 1 transmembrane glycoprotein, containing multiple leucine rich repeats within LRRCT and LRRNT domains. CD180 belongs to the toll-like receptor family and is primarily expressed in mature peripheral B cells and is thought to play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4 (UniProt: Q62192). Cross linking of CD180 with clone RP/14 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule B7.2 (Miyake et al. 1998).
ncbi gi num :
117320545
ncbi acc num :
NP_032559.2
ncbi gb acc num :
NM_008533.2
uniprot acc num :
Q62192
ncbi mol weight :
74,302 Da
ncbi pathways :
Immune System Pathway 1110668!!Innate Immune System Pathway 1110697!!Toll Like Receptor 4 (TLR4) Cascade Pathway 1110725!!Toll-Like Receptors Cascades Pathway 1110698
size :
0.25 mg
price :
755 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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