catalog number :
MBS212394
products full name :
RAT ANTI C-MYC
products short name :
C-MYC
other names :
myc proto-oncogene protein; Myc proto-oncogene protein; myc proto-oncogene protein; avian myelocytomatosis viral oncogene homolog; class E basic helix-loop-helix protein 39; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc myelocytomatosis viral oncogene homolog; v-myc avian myelocytomatosis viral oncogene homolog; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64
products gene name :
C-MYC
other gene names :
MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39
uniprot entry name :
MYC_HUMAN
specificity :
This item recognises the myc epitope which is frequently used to tag proteins, and is the same epitope recognised by clone 9E10.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Immunofluorescence (IF), Immunoprecipitation (IP), P, Western Blot (WB)
app notes :
Western Blotting: Minimum Dilution: 1/500; Maximum Dilution: 1/1000
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Amino acids 408-439 corresponding to the C-terminal region of human c-myc. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
MBS212394 recognises the myc epitope which is frequently used to tag proteins, and is the same epitope recognised by clone 9E10.
ncbi acc num :
NP_002458.2
ncbi gb acc num :
NM_002467.4
ncbi mol weight :
50,565 Da
ncbi pathways :
Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Apoptosis Pathway 198797!!Bladder Cancer Pathway 83115!!Bladder Cancer Pathway 527!!C-MYB Transcription Factor Network Pathway 138073!!C-MYC Pathway 169344!!CD40/CD40L Signaling Pathway 138061!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765
ncbi summary :
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]