product summary
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company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD89
catalog :
MBS212331
quantity :
0.1 mg
price :
300 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[MIP8a]
reactivity :
human
application :
western blot, ELISA, immunoprecipitation, flow cytometry
more info or order :
image
image 1 :
Staining of human peripheral blood granulocytes with Mouse anti Human CD89: RPE (MBS213674)
image 2 :
Staining of human peripheral blood granulocytes with Mouse anti Human CD89:Low endotoxin (MBS224611)
product information
catalog number :
MBS212331
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD89
products short name :
[CD89]
products name syn :
[Fc ALPHA R]
other names :
[immunoglobulin alpha Fc receptor isoform a; Immunoglobulin alpha Fc receptor; immunoglobulin alpha Fc receptor; Fc alpha receptor; Fc fragment of IgA, receptor for; CD_antigen: CD89]
products gene name :
[CD89]
other gene names :
[FCAR; FCAR; CD89; FcalphaRI; CD89; IgA Fc receptor]
uniprot entry name :
FCAR_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
[MIP8a]
host :
Mouse
reactivity :
Human
sequence length :
287
specificity :
Mouse anti Human CD89 antibody, clone MIP8a recognizes the human CD89 cell surface antigen, a 50-75kDa cell surface glycoprotein that is also known as the IgA receptor (Fc alphaR)
form :
Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow Cytometry, ELISA, Western Blotting, Immunoprecipitation.
app notes :
Flow Cytometry: 1/50-1/100. Use 10uL of the suggested working dilution to label 10 6 or 100uL whole blood
image1 heading :
Testing Data
image2 heading :
Testing Data
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide
other info2 :
Immunogen: Recombinant soluble human Fc alpha R. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD89 antibody, clone MIP8a recognizes the human CD89 cell surface antigen, a 50-75kDa cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R). CD89 is expressed by peripheral blood monocytes and neutrophils. MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes.
ncbi gi num :
4503673
ncbi acc num :
NP_001991.1
ncbi gb acc num :
NM_002000.3
uniprot acc num :
P24071
ncbi pathways :
Phagosome Pathway (153910); Phagosome Pathway (153859); Staphylococcus Aureus Infection Pathway (172846); Staphylococcus Aureus Infection Pathway (171867)
ncbi summary :
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
FCAR: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. 11 isoforms of the human protein are produced by alternative splicing. Protein type: Immunoglobulin superfamily; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.42. Cellular Component: integral to plasma membrane; extracellular region; plasma membrane. Molecular Function: IgA binding. Biological Process: immune response
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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