This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN MYELOPEROXIDASE
catalog :
MBS212300
quantity :
0.2 mg
price :
440 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2C7
reactivity :
human
application :
western blot, ELISA, flow cytometry, FACS, enzyme immunoassay
product information
catalog number :
MBS212300
products type :
Antibody
products full name :
MOUSE ANTI HUMAN MYELOPEROXIDASE
products short name :
MYELOPEROXIDASE
other names :
myeloperoxidase; Myeloperoxidase; myeloperoxidase; myeloperoxidase
other gene names :
MPO; MPO; MPO
uniprot entry name :
PERM_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2C7
host :
Mouse
sequence length :
777
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, ELISA (EIA), Flow cytometry (FC/FACS)*, Immunohistology Paraffin, Western Blot (WB)*
app notes :
Immunohistology - Frozen: Minimum Dilution: 1/1000; Maximum Dilution: 1/5000;. Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100; Application Note: Membrane permeabilisation is required for this application. MyBioSource recommends the use of Leucoperm for this purpose. . Immunohistology - Paraffin: Minimum Dilution: 1/500; Maximum Dilution: 1/1000;. Western Blotting: Application Note: 2C7 recognises myeloperoxidase under non-reducing conditions, see Audrian et al. for details
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G
other info2 :
Histology Positive Control Tissue: Bone marrow. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human Myeloperoxidase antibody, clone 2C7 recognizes human myeloperoxidase (MPO). MPO is an important component of azurophilic granules in neutrophils, being involved in microbicidal processes. The protein is a multimer of 2 heavy chains (55kD) and two light chains (15kD), the heavy chains being linked by a disulphide bond. Mouse anti Human Myeloperoxidase antibody, clone 2C7 recognizes native MPO in Western blots, and the heavy chain following boiling of the sample. Mouse anti Human Myeloperoxidase antibody, clone 2C7 also recognizes recombinant MPO in Western blots and weakly in ELISA. Mouse anti Human Myeloperoxidase antibody, clone 2C7 may be of value in the study of myeloid cells and myeloid leukaemias by flow cytometry following cell permeablisation.
ncbi gi num :
4557759
ncbi acc num :
NP_000241.1
ncbi gb acc num :
NM_000250.1
uniprot acc num :
P05164
ncbi mol weight :
87,248 Da
ncbi pathways :
C-MYB Transcription Factor Network Pathway 138073!!Folate Metabolism Pathway 198833!!IL23-mediated Signaling Events Pathway 138000!!Phagosome Pathway 153910!!Phagosome Pathway 153859!!Selenium Pathway 198825!!Transcriptional Misregulation In Cancer Pathway 523016!!Transcriptional Misregulation In Cancer Pathway 522987!!Vitamin B12 Metabolism Pathway 920974!!Amb2 Integrin Signaling Pathway 137945
ncbi summary :
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
size :
0.2 mg
price :
440 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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