catalog number :
MBS212291
products full name :
MOUSE ANTI RAT BETA 2 MICROGLOBULIN
products short name :
BETA 2 MICROGLOBULIN
other names :
beta-2-microglobulin; Beta-2-microglobulin; beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA); beta-2 microglobulin; N/A
other gene names :
B2m; B2m; N/A
uniprot entry name :
B2MG_RAT
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/20
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G
other info2 :
Immunogen: Rat microglial cells. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse MOM myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Rat
products description :
Mouse anti Rat beta 2 Microglobulin antibody, clone TLD-3H12B recognizes native beta 2 microglobulin which is a component of MHC class I molecules, which are present on all nucleated cells. Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients. Also known as B2M, it has been suggested that this protein can be used as a prognostic marker for HIV infection.
ncbi acc num :
NP_036644.1
ncbi gb acc num :
NM_012512.2
ncbi mol weight :
13,720 Da
ncbi pathways :
Adaptive Immune System Pathway 1121508!!Amyloids Pathway 1121861!!Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway 1121527!!Antigen Processing And Presentation Pathway 83466!!Antigen Processing And Presentation Pathway 485!!Antigen Processing-Cross Presentation Pathway 1121528!!Class I MHC Mediated Antigen Processing Presentation Pathway 1121525!!DAP12 Interactions Pathway 1121612!!DAP12 Signaling Pathway 1121613!!Disease Pathway 1121849
ncbi summary :
mouse homolog plays a role in the assembly and surface expression of MHC class I molecules [RGD, Feb 2006]