catalog number :
MBS212282
products full name :
MOUSE ANTI HUMAN CD44v6
products short name :
CD44v6
other names :
CD44 antigen isoform 1; CD44 antigen; CD44 antigen; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; epican; extracellular matrix receptor III; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; homing function and Indian blood group system; hyaluronate receptor; phagocytic glycoprotein 1; CD44 molecule (Indian blood group); CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD_antigen: CD44
products gene name :
CD44v6
other gene names :
CD44; CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I
uniprot entry name :
CD44_HUMAN
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Flow cytometry (FC/FACS), Immunohistology Paraffin*, Western Blot (WB)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Immunohistology - Frozen: Minimum Dilution: 1/400; Maximum Dilution: 1/500. Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/200. Immunohistology - Paraffin: Maximum Dilution: 1/200; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
other info2 :
Immunogen: Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of human CD44. Fusion Partners: Spleen cells from immunised BALB/c micewere fused with cells of the P3X63Ag8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD44v6 antibody, clone VFF-7 specifically recognizes an epitope encoded by exon v6 on the variant portion of human CD44.
ncbi acc num :
NP_000601.3
ncbi gb acc num :
NM_000610.3
ncbi mol weight :
15,635 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway 106062!!Cytokine Signaling In Immune System Pathway 366171!!Defective B3GAT3 Causes JDSSDHD Pathway 1127588!!Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway 1127592!!Defective B4GALT7 Causes EDS, Progeroid Type Pathway 1127587!!Defective CHST14 Causes EDS, Musculocontractural Type Pathway 1127591!!Defective CHST3 Causes SEDCJD Pathway 1127590!!Defective CHST6 Causes MCDC1 Pathway 1127593!!Defective CHSY1 Causes TPBS Pathway 1127589!!Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway 1127594
ncbi summary :
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]