product summary
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company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI SHEEP INTERLEUKIN-8
catalog :
MBS212255
quantity :
0.25 mg
price :
625 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8M6
reactivity :
sheep
application :
western blot, ELISA, flow cytometry, FACS, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS212255
products type :
Antibody
products full name :
MOUSE ANTI SHEEP INTERLEUKIN-8
products short name :
IL-8
other names :
interleukin-8; Interleukin-8; interleukin-8; C-X-C motif chemokine 8; IL-8; chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8
other gene names :
CXCL8; CXCL8; IL8; IL8; IL-8
uniprot entry name :
IL8_SHEEP
clonality :
Monoclonal
isotype :
IgG2a
clone :
8M6
host :
Mouse
reactivity :
Bovine, Dog, Ferret, Mink, Mustelid, Pig, Rabbit
sequence length :
101
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Flow cytometry (FC/FACS)*, Western Blot (WB)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. ELISA: Maximum Dilution: 5ug/ml. Flow Cytometry: Maximum Dilution: 1/10; Application Note: Membrane permeabilization is required for this application. MyBioSource recommend the use of Leucoperm
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Sheep
products description :
Mouse anti Ovine Interleukin-8 antibody, clone 8M6 recognizes ovine interleukin-8 (IL-8), also known as C-X-C motif chemokine 8. IL-8 is a 101amino acid ~16kDa chemoattractant for neutrophils, basophils and T-cells. IL-8 is produced by several cell types including neutrophils, monocytes and macrophages in response to inflammatory stimulation. Mouse anti ovine Interleukin-8 antibody, clone 8M6 shows no cross-reactivity with ovine IL-1 beta, IL-6, MCP-1 or TNF alpha. Responses to infectious stimuli may vary among ovine species, the response to Mannheimia haemolytica, a causitive agent of pneumonia, peritonitis and gangrenous mastitis in ovids, is exagerrated in Bighorn sheep (Ovis canadensis) compared to domestic sheep (Ovis aries) with significantly elevated IL-8 levels in response to infection (Herndon et al. 2010). Mouse anti ovine interleukin-8 antibody, clone 8M6 has been utilized to identify cells and cell types expressing IL-8 in inflamed porcine tissue (Laursen et al. 2014) showing here also that neutrophils are the predominant cell type expressing IL-8 whilst epithelial and endothelial cells in the vicinity of inflammatory lesions also express the cytokine. Clone 8M6 neutralizes the bioactivity of ovine IL-8.Note: Removal of the preservative is recommended prior to use in functional assays - MyBioSource recommend the use of a Slide-A-Lyser dialysis cassette for this purpose.
ncbi gi num :
57164403
ncbi acc num :
NP_001009401.1
ncbi gb acc num :
NM_001009401.2
uniprot acc num :
P36925
ncbi mol weight :
11,292 Da
ncbi pathways :
Amoebiasis Pathway (1030877); Amoebiasis Pathway (167191); Bladder Cancer Pathway (1030899); Bladder Cancer Pathway (527); Chagas Disease (American Trypanosomiasis) Pathway (1030871); Chagas Disease (American Trypanosomiasis) Pathway (147795); Chemokine Signaling Pathway (1030749); Chemokine Signaling Pathway (96864); Cytokine-cytokine Receptor Interaction Pathway (1030752); Cytokine-cytokine Receptor Interaction Pathway (460)
size1 :
0.25 mg
price1 :
625 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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