This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD40
catalog :
MBS212239
quantity :
0.2 mg
price :
415 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
LOB7/6
reactivity :
human, dog
application :
immunoprecipitation, flow cytometry, FACS
product information
catalog number :
MBS212239
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD40
products short name :
CD40
other names :
tumor necrosis factor receptor superfamily member 5 isoform 1; Tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; B cell surface antigen CD40; B cell-associated molecule; CD40 antigen (TNF receptor superfamily member 5); CD40 type II isoform; CD40L receptor; nerve growth factor receptor-related B-lymphocyte activation molecule; CD40 molecule, TNF receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD_antigen: CD40
products gene name :
CD40
other gene names :
CD40; CD40; p50; Bp50; CDW40; TNFRSF5; TNFRSF5
uniprot entry name :
TNR5_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
LOB7/6
host :
Mouse
reactivity :
Dog
sequence length :
277
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistology Paraffin*
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Immunohistology - Frozen: Minimum Dilution: 1ug/ml; Maximum Dilution: 10ug/ml. Flow Cytometry: Maximum Dilution: 20ug/ml. Immunohistology - Paraffin: Minimum Dilution: 1ug/ml; Maximum Dilution: 10ug/ml; Application Note: This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein A
other info2 :
Immunogen: CD40 Ig(Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG. Histology Positive Control Tissue: Human Tonsil. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line. Buffer Solution: Tris buffered saline. Target Species: Human
ncbi gi num :
4507581
ncbi acc num :
NP_001241.1
ncbi gb acc num :
NM_001250.5
ncbi mol weight :
22,259 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Allograft Rejection Pathway 920963!!Allograft Rejection Pathway 83123!!Allograft Rejection Pathway 535!!Asthma Pathway 83120!!Asthma Pathway 532!!Autoimmune Thyroid Disease Pathway 83121!!Autoimmune Thyroid Disease Pathway 533!!CD40/CD40L Signaling Pathway 138061!!Cell Adhesion Molecules (CAMs) Pathway 83069
ncbi summary :
This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014]
size :
0.2 mg
price :
415 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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