antibody

RAT ANTI MOUSE INTERLEUKIN-5

MBS212179

0.5 mg

670 USD

monoclonal

rat

nonconjugated

[TRFK5]

human, mouse

western blot, ELISA, flow cytometry, FACS, enzyme immunoassay

Antibody

RAT ANTI MOUSE INTERLEUKIN-5

[IL-5]

[interleukin-5; Interleukin-5; interleukin-5; B-cell growth factor II; BCGF-II; T-cell replacing factor; TRF; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor; interleukin 5; B-cell growth factor II; BCGF-II; Cytotoxic T-lymphocyte inducer; Eosinophil differentiation factor; T-cell replacing factor; TRF]

[Il5; Il5; Il-5; Il-5; IL-5; BCGF-II; TRF]

IL5_MOUSE

Monoclonal

IgG1

[TRFK5]

Rat

Guinea Pig, Human, Pig

133

Purified. Purified IgG - liquid

IgG concentration 0.5 mg/ml

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

ELISA (EIA), Flow cytometry (FC/FACS)*, Western Blot (WB)

Flow Cytometry: Application Note: Membrane permeabilisation is required for this application. MyBioSource recommends the use of Leucoperm for this purpose.

Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Purified natural murine IL-5. Buffer Solution: Phosphate buffered saline. Target Species: Mouse

Rat anti mouse IL-5, clone TRFK5 recognizes mouse interleukin-5. IL-5 is a regulatory cytokine that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. Rat anti mouse IL-5, clone TRFK5 may be used to neutralize IL-5 bioactivity in a functional assay (Schumacher. et al. 1988) and Abrams et al. 1992).

6754336

NP_034688.1

NM_010558.1

P04401

15,410 Da

Allograft Rejection Pathway (83316); Allograft Rejection Pathway (535); Asthma Pathway (83313); Asthma Pathway (532); Autoimmune Thyroid Disease Pathway (83314); Autoimmune Thyroid Disease Pathway (533); Cytokine Signaling In Immune System Pathway (1110778); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response (BioCarta) Pathway (198283)

IL5: Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. Belongs to the IL-5 family. Protein type: Secreted, signal peptide; Cytokine; Secreted. Cellular Component: extracellular space; extracellular region. Molecular Function: interleukin-5 receptor binding; growth factor activity; cytokine activity. Biological Process: positive regulation of peptidyl-tyrosine phosphorylation; cytokine and chemokine mediated signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of B cell proliferation; positive regulation of JAK-STAT cascade; immune response; positive regulation of transcription factor activity; positive regulation of immunoglobulin secretion; positive regulation of eosinophil differentiation

0.5 mg

670 USD