product summary
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company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI PI-3 KINASE p85 SUBUNIT BETA
catalog :
MBS212045
quantity :
0.1 mg
price :
405 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
T15
reactivity :
mouse
application :
western blot, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS212045
products type :
Antibody
products full name :
MOUSE ANTI PI-3 KINASE p85 SUBUNIT BETA
products short name :
PI-3 KINASE p85 SUBUNIT BETA
other names :
phosphatidylinositol 3-kinase regulatory subunit beta; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase regulatory subunit beta; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K regulatory subunit beta; phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; ptdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit p85-beta
other gene names :
Pik3r2; Pik3r2; p85beta; PI3-kinase regulatory subunit beta; PI3K regulatory subunit beta; PtdIns-3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit p85-beta
uniprot entry name :
P85B_MOUSE
clonality :
Monoclonal
isotype :
IgG1
clone :
T15
host :
Mouse
sequence length :
722
form :
Purified. Purified IgG - liquid
concentration :
Approximate Protein Concentration: 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB)
app notes :
Immunoprecipitation: Maximum Dilution: 10 ug/ml;. Western Blotting: Minimum Dilution: 1/500; Maximum Dilution: 1/1000
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
other info2 :
Immunogen: Balculovirus expressed (Recombinant) p85 beta subunit of bovine PI-3 kinase. Fusion Partners: Spleen cells from immunised mice were fused with cells of the NS1 mouse myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Bovine
products description :
Mouse anti PI-3 Kinase p85 Subunit beta antibody, clone T15 recognizes the p85 subunit of bovine PI-3 kinase.
ncbi gi num :
244792921
ncbi acc num :
NP_032867.2
ncbi gb acc num :
NM_008841.2
ncbi mol weight :
81,266 Da
ncbi pathways :
3-phosphoinositide Biosynthesis Pathway (542898); AMPK Signaling Pathway (989651); AMPK Signaling Pathway (992181); Acute Myeloid Leukemia Pathway (83310); Acute Myeloid Leukemia Pathway (529); Adaptive Immune System Pathway (1110669); Adrenergic Signaling In Cardiomyocytes Pathway (908268); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Aldosterone-regulated Sodium Reabsorption Pathway (130627); Aldosterone-regulated Sodium Reabsorption Pathway (130590)
uniprot summary :
PIK3R2: regulatory subunit of phosphoinositide-3-kinase. Mediates binding to a subset of tyrosine-phosphorylated proteins through its SH2 domain. Acts as an adapter, mediating the association of the p110 catalytic unit of the alpha, beta and delta enzymes to the plasma membrane, where p110 phosphorylates inositol lipids. May play an additional role in the regulation of the actin cytoskeleton. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Its SH2 domains interacts with the YTHM motif of phosphorylated INSR in vitro. Defects in PIK3R1 are a cause of severe insulin resistance. Four alternatively spliced isoforms have been described. Protein type: Motility/polarity/chemotaxis; Kinase, lipid. Cellular Component: intracellular; phosphoinositide 3-kinase complex; nucleus. Molecular Function: protein binding; protein heterodimerization activity; 1-phosphatidylinositol-3-kinase activity; phosphoinositide 3-kinase regulator activity; receptor tyrosine kinase binding; transcription factor binding; protein phosphatase binding. Biological Process: phosphoinositide 3-kinase cascade; protein transport; cellular response to insulin stimulus; regulation of phosphorylation; transport; insulin receptor signaling pathway; positive regulation of transcription factor import into nucleus; cell glucose homeostasis; regulation of autophagy; positive regulation of transcription from RNA polymerase II promoter; signal transduction
size1 :
0.1 mg
price1 :
405 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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