catalog number :
MBS212000
products full name :
MOUSE ANTI hCG (ALPHA 5 EPITOPE)
products short name :
hCG
other names :
glycoprotein hormones alpha chain isoform 2; Glycoprotein hormones alpha chain; glycoprotein hormones alpha chain; FSH-alpha; LSH-alpha; TSH-alpha; anterior pituitary glycoprotein hormones common subunit alpha; choriogonadotropin alpha chain; chorionic gonadotrophin subunit alpha; chorionic gonadotropin, alpha polypeptide; follicle-stimulating hormone alpha chain; follicle-stimulating hormone alpha subunit; follitropin alpha chain; luteinizing hormone alpha chain; lutropin alpha chain; thyroid-stimulating hormone alpha chain; thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain
other gene names :
CGA; CGA; HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA; CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha
uniprot entry name :
GLHA_HUMAN
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Immunoassay (IY), Radioimmunoassays (RIA), Western Blot (WB)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein A
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti hCG (alpha 5 Epitope) antibody, clone INN-hFSH-158 recognizes the alpha 5 epitope on the alpha subunit of hCG, hLH, hFSH, hISH and the free alpha subunit. The alpha 5 epitope is destroyed upon iodination.
ncbi acc num :
NP_000726.1
ncbi gb acc num :
NM_000735.3
ncbi mol weight :
13,075 Da
ncbi pathways :
Amine-derived Hormones Pathway (160983); Androgen Biosynthesis Pathway (106154); Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); FSH Signaling Pathway (672455); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548)
ncbi summary :
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
uniprot summary :
CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q12-q21. Cellular Component: extracellular region. Molecular Function: protein binding; hormone activity. Biological Process: cellular protein metabolic process; cell-cell signaling; peptide hormone processing; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration