MOUSE ANTI hCG (ALPHA 4 EPITOPE) | MyBioSource MBS211999 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MOUSE ANTI hCG (ALPHA 4 EPITOPE)

catalog :

MBS211999

quantity :

0.5 mg

price :

405 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

INN-hFSH-132

reactivity :

human

application :

western blot, ELISA, immunoprecipitation, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS211999

products type :

Antibody

products full name :

MOUSE ANTI hCG (ALPHA 4 EPITOPE)

products short name :

hCG

other names :

glycoprotein hormones alpha chain isoform 2; Glycoprotein hormones alpha chain; glycoprotein hormones alpha chain; FSH-alpha; LSH-alpha; TSH-alpha; anterior pituitary glycoprotein hormones common subunit alpha; choriogonadotropin alpha chain; chorionic gonadotrophin subunit alpha; chorionic gonadotropin, alpha polypeptide; follicle-stimulating hormone alpha chain; follicle-stimulating hormone alpha subunit; follitropin alpha chain; luteinizing hormone alpha chain; lutropin alpha chain; thyroid-stimulating hormone alpha chain; thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain

products gene name :

hCG

other gene names :

CGA; CGA; HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA; CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha

uniprot entry name :

GLHA_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

INN-hFSH-132

host :

Mouse

sequence length :

116

specificity :

A high affinity antibody recognising the alpha 4 epitope of the alpha-subunit of Human Chorionic Gonadotrophin (hCG), hLH, hFSH, hTSH and free alpha-subunit. The recognised epitope comprises amino-acids alpha 15 to alpha 22 of the human sequence.

form :

Purified. Purified IgG - liquid

concentration :

IgG concentration 1 mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

ELISA (EIA), Immunoprecipitation (IP), Immunohistology Paraffin*, Western Blot (WB)

app notes :

Immunohistology - Paraffin: Application Note: This product requires antigen retrieval using steam heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.

other info1 :

Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by ion exchange chromatography

other info2 :

Immunogen: Human Follicle Stimulating Hormone (FSH). Fusion Partners: Spleen cells from immunised mice were fused with cells of the X63-Ag8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human

products description :

ncbi gi num :

4502787

ncbi acc num :

NP_000726.1

ncbi gb acc num :

NM_000735.3

uniprot acc num :

P01215

ncbi mol weight :

13,075 Da

ncbi pathways :

Amine-derived Hormones Pathway (160983); Androgen Biosynthesis Pathway (106154); Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); FSH Signaling Pathway (672455); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548)

ncbi summary :

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

uniprot summary :

CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6q12-q21. Cellular Component: extracellular region. Molecular Function: protein binding; hormone activity. Biological Process: cellular protein metabolic process; cell-cell signaling; positive regulation of cell proliferation; peptide hormone processing; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration

size1 :

0.5 mg

price1 :

405 USD

more info or order :

MyBioSource product webpage