antibody

MOUSE ANTI TROPONIN I (CARDIAC/SKELETAL)

MBS211970

0.2 mg

320 USD

monoclonal

mouse

nonconjugated

C5

human, mouse, rat, dog, cow

western blot, ELISA, enzyme immunoassay

Antibody

MOUSE ANTI TROPONIN I (CARDIAC/SKELETAL)

TROPONIN I

troponin I, fast skeletal muscle isoform 1; Troponin I, fast skeletal muscle; troponin I, fast skeletal muscle; troponin I fast twitch 2; troponin I, fast-twitch isoform; troponin I, fast-twitch skeletal muscle isoform; troponin I, skeletal, fast; troponin I type 2 (skeletal, fast); Troponin I, fast-twitch isoform

TNNI2; TNNI2; DA2B; FSSV; fsTnI; AMCD2B

TNNI2_HUMAN

Monoclonal

IgG2b

C5

Mouse

Bovine, Cat, Dog, Fish, Goat, Mouse, Pig, Rabbit, Rat

182

Purified. Purified Ig - liquid

Approximate Protein Concentration: 1 mg/ml

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

ELISA (EIA), Western Blot (WB)

Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified Ig prepared by affinity chromatography on Protein A

Immunogen: Free human cardiac troponin I. Buffer Solution: Phosphate buffered saline. Target Species: Human

Mouse anti Troponin I (Cardiac/Skeletal) antibody, clone C5 reacts with cardiac and skeletal troponin I. Mouse anti Troponin I (Cardiac/Skeletal) antibody, clone C5 recognizes an epitope between amino acids 186-192 of cardiac troponin I.Troponin I is 1 of 3 subunits that constitute the troponin complex which plays an important role in the regulation of skeletal and cardiac muscle contraction. It is presented in cardiac tissue by a single isoform with a molecular weight of 29 kDa and is known as a specific marker for cardiac tissue damage.

224967057

NP_001139301.1

NM_001145829.1

21,355 Da

Muscle Contraction Pathway 106261!!Striated Muscle Contraction Pathway 198903!!Striated Muscle Contraction Pathway 106262

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]

0.2 mg

320 USD