MOUSE ANTI HUMAN GM-CSF | MyBioSource MBS211665 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

MOUSE ANTI HUMAN GM-CSF

catalog :

MBS211665

quantity :

0.1 mg

price :

500 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3209

reactivity :

human, mouse

application :

western blot, ELISA, enzyme immunoassay

product information

catalog number :

MBS211665

products type :

Antibody

products full name :

MOUSE ANTI HUMAN GM-CSF

products short name :

GM-CSF

other names :

granulocyte-macrophage colony-stimulating factor; Granulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony-stimulating factor; CSF; granulocyte macrophage-colony stimulating factor; molgramostin; sargramostim; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; Molgramostin; Sargramostim

products gene name :

GM-CSF

other gene names :

CSF2; CSF2; GMCSF; GMCSF; GM-CSF; CSF

uniprot entry name :

CSF2_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

3209 (30-4)

host :

Mouse

reactivity :

Mouse (Weak)

sequence length :

144

specificity :

This item recognises recombinant and native human granulocyte macrophage colony stimulating factor (GM-CSF). Human Granulocyte colony stimulating factor (GM-CSF) is a 14.6kDa glycoprotein, which is produced by T cells, macrophages, fibroblasts and endothelial cells. GM-CSF is involved in the stimulation of proliferation and differentiation of granulocyte and macrophage progenitor cells.The neutralisation dose (ND50) of this batch, as determined by the proliferation of TF-1 cells, is approximately 0.3-0.5 ug/ml in the presence of 0.5 ng/ml of recombinant human GM-CSF. The ND50 may vary depending on conditions.

form :

Purified. Purified IgG - liquid

concentration :

IgG concentration 1.0 mg/ml

storage stability :

Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

Immunohistology Frozen, ELISA (EIA), Functional Assays (FN), Western Blot (WB)*

app notes :

Immunohistology - Frozen: Minimum Dilution: 8.0; Maximum Dilution: 25 ug/ml;. ELISA: Minimum Dilution: 0.5; Maximum Dilution: 1.0 ug/ml;. Functional Assays: Minimum Dilution: 0.3; Maximum Dilution: 0.5 ug/ml;. Western Blotting: Minimum Dilution: 1.0; Maximum Dilution: 2.0 ug/ml; Application Note: 4740-0955 should be used under non-reducing conditions, reducing conditions are not recommended.

other info1 :

Perservative Stabilisers: 1% trehalose. Preparation: Purified IgG prepared by affinity chromatography on Protein A.

other info2 :

Immunogen: Recombinant protein corresponding to amino acids 14 to 144 of human GM-CSF produced in E Coli. Buffer Solution: Phosphate buffered saline. Target Species: Human

products description :

MBS211665 recognises recombinant and native human granulocyte macrophage colony stimulating factor (GM-CSF). Human Granulocyte colony stimulating factor (GM-CSF) is a 14.6kDa glycoprotein, which is produced by T cells, macrophages, fibroblasts and endothelial cells. GM-CSF is involved in the stimulation of proliferation and differentiation of granulocyte and macrophage progenitor cells.The neutralisation dose (ND50) of this batch, as determined by the proliferation of TF-1 cells, is approximately 0.3-0.5 ug/ml in the presence of 0.5 ng/ml of recombinant human GM-CSF. The ND50 may vary depending on conditions.

ncbi gi num :

27437030

ncbi acc num :

NP_000749.2

ncbi gb acc num :

NM_000758.3

uniprot acc num :

P04141

ncbi mol weight :

16,295 Da

ncbi pathways :

Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Calcium Signaling In The CD4+ TCR Pathway 137941!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response Pathway 198794!!Fc Epsilon RI Signaling Pathway 83082!!Fc Epsilon RI Signaling Pathway 493

ncbi summary :

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

500 USD