catalog number :
MBS211555
products full name :
MOUSE ANTI CORTISOL
products short name :
[CORTISOL]
reactivity :
Human; N.B. Antibody reactivity and working may vary between species
form :
Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
app notes :
Suggested Dilution: 1/50-1/500
other info1 :
Preservative Stabilisers: 0.09% Sodium Azide (NaN3): Preparation: Purified IgG prepared by affinity chromatography on Protein A. Immunogen: Cortisol conjugated to bovine serum albumin
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Broad
products description :
Mouse anti cortisol monoclonal antibody, clone C13 recognizes cortisol, a glucocorticoid hormone synthesized from cholesterol by the adrenal cortex. It is released in response to pituitary adenocorticotrophic hormone (ACTH) which is, in turn, regulated by corticotrophin releasing factor (CRF). High levels of cortisol act to regulate the release of ACTH and CRF via negative feedback inhibition. The release of cortisol stimulates the conversion of proteins to carbohydrates, raises blood sugar levels and promotes glycogen storage in the liver. The following cross reactivities were observed:. Cortisol: 100%. Prednisolone: 30%. Cortisone: 25%. Corticosterone: 10%. 11-desoxycortisol: 5%. No reactivity was observed with 17-a-OH-progesterone.