catalog number :
MBS211440
products full name :
MOUSE ANTI HUMAN OSTEOCALCIN
products short name :
OSTEOCALCIN
other names :
osteocalcin preproprotein; Osteocalcin; osteocalcin; bone Gla protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate (gla) protein; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
other gene names :
BGLAP; BGLAP; OC; BGP; OCN; BGP
uniprot entry name :
OSTCN_HUMAN
reactivity :
Bovine, Pig, Rabbit, Rat
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human Osteocalcin antibody, clone 8H12F9H10 recognizes intact human and bovine osteocalcin in a 2 site assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-43 or intact bovine osteocalcin.Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget's disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
ncbi acc num :
NP_954642.1
ncbi gb acc num :
NM_199173.4
ncbi mol weight :
10,963 Da
ncbi pathways :
FGF Signaling Pathway 137989!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Interleukin-11 Signaling Pathway 698753!!Notch-mediated HES/HEY Network Pathway 169347!!Regulation Of Retinoblastoma Protein Pathway 137916!!Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway 169349